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- W2951675361 abstract "Abstract In order to produce movements, muscles must act through joints. The translation from muscle force to limb movement is mediated by internal joint structures that permit movement in some directions but constrain it in others. Although muscle forces acting against constrained directions will not affect limb movements, such forces can cause excess stresses and strains in joint structures, leading to pain or injury. In this study, we hypothesized that the central nervous system (CNS) chooses muscle activations to avoid excess joint stresses and strains. We evaluated this hypothesis by examining adaptation strategies after selective paralysis of a muscle acting at the rat knee. We show that the CNS compromises between restoration of task performance and regulation of joint stresses and strains. These results have significant implications to our understanding of the neural control of movements, suggesting that common theories emphasizing task performance are insufficient to explain muscle activations during behaviors." @default.
- W2951675361 created "2019-06-27" @default.
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- W2951675361 date "2018-05-02" @default.
- W2951675361 modified "2023-09-27" @default.
- W2951675361 title "Adaptation after vastus lateralis denervation in rats suggests neural regulation of joint stresses and strains" @default.
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- W2951675361 doi "https://doi.org/10.1101/312488" @default.
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