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- W2951723401 abstract "Significance The cell wall is a thin polymeric layer encasing the membrane of bacterial, fungal, and vegetal cells, which supports viability and defines cell shape and the mode of growth and division. The material properties of the cell wall are thus key for understanding morphogenesis, but remain difficult to quantify. We introduce a systematic method to map subcellular values of cell wall thickness and bulk elasticity in large populations of yeast cells with unprecedented accuracy. By screening libraries of mutants with defects in cell shapes, we demonstrate that cell walls are stiffer in larger cells or larger cell portions. This size-dependent stiffening constrains cell size definition and promotes cell mechanical integrity." @default.
- W2951723401 created "2019-06-27" @default.
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- W2951723401 date "2019-06-24" @default.
- W2951723401 modified "2023-10-14" @default.
- W2951723401 title "Systematic mapping of cell wall mechanics in the regulation of cell morphogenesis" @default.
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- W2951723401 doi "https://doi.org/10.1073/pnas.1820455116" @default.
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