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• W2951744922 endingPage "4472" @default.
• W2951744922 startingPage "4466" @default.
• W2951744922 abstract "The regioselective carbonylation of unactivated C(sp3)–H bonds of aliphatic amides, using 2-pyridinylmethylamine as a directing group in conjunction with Ru3(CO)12 as a catalyst is described. The presence of a 2-pyridinylmethylamine moiety in the amides is crucial for the success of the reaction. Although ethylene is not incorporated into the products, its presence is also essential for the reaction to proceed. Furthermore, the addition of H2O is important for the reaction to proceed efficiently. The reaction shows a high preference for the C–H bonds of methyl groups, compared to methylene C–H bonds, even the methylene C–H bonds are activated by the presence of an oxygen atom or an aryl group. In addition, the reaction tolerates various functional groups, such as MeO, Cl, CF3, CN, and even Br substituents. The reaction of α-mono-substituted aliphatic amides gave the corresponding carbonylation products in lower yields, although the use of α,α-di-substituted aliphatic amides resulted in high product yields. The use of a sterically demanding directing group, such as 1-(2-pyridinylethyl)amine moiety, in α-mono-substituted aliphatic amides improved the yields of the products. The stoichiometric reaction of an amide with Ru3(CO)12 gave a stable di-nuclear ruthenium complex as a single ruthenium complex in which the 2-pyridinylmethylamino moiety is coordinated to the ruthenium center in a N,N-manner and an amide carbonyl oxygen binds to the other ruthenium center, but C–H bond activation is not involved. The complex itself does not show catalytic activity, but is activated in the presence of H2O under the catalytic reaction conditions employed." @default.
• W2951744922 created "2019-06-27" @default.
• W2951744922 creator A5019807980 @default.
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• W2951744922 date "2013-06-01" @default.
• W2951744922 modified "2023-09-30" @default.
• W2951744922 title "Ruthenium-catalyzed cyclocarbonylation of aliphatic amides through the regioselective activation of unactivated C(sp3)–H bonds" @default.
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• W2951744922 cites W1978976844 @default.
• W2951744922 cites W1979480323 @default.
• W2951744922 cites W1983576974 @default.
• W2951744922 cites W1985733865 @default.
• W2951744922 cites W1991200342 @default.
• W2951744922 cites W1994390276 @default.
• W2951744922 cites W1996928099 @default.
• W2951744922 cites W2002525719 @default.
• W2951744922 cites W2003577473 @default.
• W2951744922 cites W2006842723 @default.
• W2951744922 cites W2008648562 @default.
• W2951744922 cites W2009737380 @default.
• W2951744922 cites W2015739112 @default.
• W2951744922 cites W2016902320 @default.
• W2951744922 cites W2018301329 @default.
• W2951744922 cites W2037032992 @default.
• W2951744922 cites W2039386332 @default.
• W2951744922 cites W2050605218 @default.
• W2951744922 cites W2050791488 @default.
• W2951744922 cites W2051418642 @default.
• W2951744922 cites W2051800512 @default.
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• W2951744922 cites W2066309940 @default.
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• W2951744922 cites W2072380392 @default.
• W2951744922 cites W2078442327 @default.
• W2951744922 cites W2083044747 @default.
• W2951744922 cites W2086165010 @default.
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• W2951744922 cites W2096579838 @default.
• W2951744922 cites W2099349445 @default.
• W2951744922 cites W2099534742 @default.
• W2951744922 cites W2103031974 @default.
• W2951744922 cites W2129464611 @default.
• W2951744922 cites W2131913282 @default.
• W2951744922 cites W2132328311 @default.
• W2951744922 cites W2135417469 @default.
• W2951744922 cites W2136935607 @default.
• W2951744922 cites W2143403265 @default.
• W2951744922 cites W2144577976 @default.
• W2951744922 cites W2144600480 @default.
• W2951744922 cites W2148701450 @default.
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• W2951744922 cites W2161960052 @default.
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• W2951744922 cites W2168800983 @default.
• W2951744922 cites W2316864204 @default.
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• W2951744922 cites W4366076375 @default.
• W2951744922 cites W4382498853 @default.
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• W2951744922 doi "https://doi.org/10.1016/j.tet.2013.02.006" @default.
• W2951744922 hasPublicationYear "2013" @default.
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