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• W2951764080 endingPage "2198.e3" @default.
• W2951764080 startingPage "2190" @default.
• W2951764080 abstract "Dopamine is integral to attentional and motivational processes, but studies are largely restricted to the central nervous system. In mammals [1, 2] and fishes [3, 4], central dopaminergic neurons project to the inner ear and could modulate acoustic signals at the earliest stages of processing. Studies in rodents show dopamine inhibits cochlear afferent neurons and protects against noise-induced acoustic injury [5-10]. However, other functions for inner ear dopamine have not been investigated, and the effect of dopamine on peripheral auditory processing in non-mammalians remains unknown [11, 12]. Insights could be gained by studies conducted in the context of intraspecific acoustic communication. We present evidence from a vocal fish linking reproductive-state-dependent changes in auditory sensitivity with seasonal changes in the dopaminergic efferent system in the saccule, their primary organ of hearing. Plainfin midshipman (Porichthys notatus) migrate from deep-water winter habitats to the intertidal zone in the summer to breed. Nesting males produce nocturnal vocalizations to attract females [13]. Both sexes undergo seasonal enhancement of hearing sensitivity at the level of the hair cell [14-16], increasing the likelihood of detecting conspecific signals [17, 18]. Importantly, reproductive females concurrently have reduced dopaminergic input to the saccule [19]. Here, we show that dopamine decreases saccule auditory sensitivity via a D2-like receptor. Saccule D2a receptor expression is reduced in the summer and correlates with sensitivity within and across seasons. We propose that reproductive-state-dependent changes to the dopaminergic efferent system provide a release of inhibition in the saccule, enhancing peripheral encoding of social-acoustic signals." @default.
• W2951764080 created "2019-06-27" @default.
• W2951764080 creator A5017613722 @default.
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• W2951764080 creator A5074408548 @default.
• W2951764080 date "2019-07-01" @default.
• W2951764080 modified "2023-10-01" @default.
• W2951764080 title "Forebrain Dopamine System Regulates Inner Ear Auditory Sensitivity to Socially Relevant Acoustic Signals" @default.
• W2951764080 cites W1520850286 @default.
• W2951764080 cites W1541123999 @default.
• W2951764080 cites W1565997775 @default.
• W2951764080 cites W1635022045 @default.
• W2951764080 cites W1910066986 @default.
• W2951764080 cites W1967474964 @default.
• W2951764080 cites W1968917001 @default.
• W2951764080 cites W1970540804 @default.
• W2951764080 cites W1971342187 @default.
• W2951764080 cites W1977720783 @default.
• W2951764080 cites W1980057229 @default.
• W2951764080 cites W1982633796 @default.
• W2951764080 cites W1984553370 @default.
• W2951764080 cites W1986918612 @default.
• W2951764080 cites W1991528713 @default.
• W2951764080 cites W1992380956 @default.
• W2951764080 cites W1993948693 @default.
• W2951764080 cites W1995913178 @default.
• W2951764080 cites W1998918821 @default.
• W2951764080 cites W2001947879 @default.
• W2951764080 cites W2003130300 @default.
• W2951764080 cites W2007556539 @default.
• W2951764080 cites W2010541229 @default.
• W2951764080 cites W2016412437 @default.
• W2951764080 cites W2017461503 @default.
• W2951764080 cites W2023601013 @default.
• W2951764080 cites W2023961768 @default.
• W2951764080 cites W2026421805 @default.
• W2951764080 cites W2027815171 @default.
• W2951764080 cites W2028461984 @default.
• W2951764080 cites W2033867287 @default.
• W2951764080 cites W2034132865 @default.
• W2951764080 cites W2036861275 @default.
• W2951764080 cites W2040030077 @default.
• W2951764080 cites W2046440640 @default.
• W2951764080 cites W2049990850 @default.
• W2951764080 cites W2050127427 @default.
• W2951764080 cites W2052291748 @default.
• W2951764080 cites W2053977439 @default.
• W2951764080 cites W2060340636 @default.
• W2951764080 cites W2063408409 @default.
• W2951764080 cites W2063582768 @default.
• W2951764080 cites W2065122532 @default.
• W2951764080 cites W2065600804 @default.
• W2951764080 cites W2069519495 @default.
• W2951764080 cites W2074979045 @default.
• W2951764080 cites W2076909523 @default.
• W2951764080 cites W2080661030 @default.
• W2951764080 cites W2083137140 @default.
• W2951764080 cites W2086645169 @default.
• W2951764080 cites W2087896850 @default.
• W2951764080 cites W2091649963 @default.
• W2951764080 cites W2096193724 @default.
• W2951764080 cites W2097744565 @default.
• W2951764080 cites W2106495485 @default.
• W2951764080 cites W2107742702 @default.
• W2951764080 cites W2112494376 @default.
• W2951764080 cites W2132610577 @default.
• W2951764080 cites W2138581811 @default.
• W2951764080 cites W2138610428 @default.
• W2951764080 cites W2139316317 @default.
• W2951764080 cites W2142413352 @default.
• W2951764080 cites W2151661207 @default.
• W2951764080 cites W2154563297 @default.
• W2951764080 cites W2159376921 @default.
• W2951764080 cites W2162849654 @default.
• W2951764080 cites W2168625874 @default.
• W2951764080 cites W2174592092 @default.
• W2951764080 cites W2210501053 @default.
• W2951764080 cites W2222417652 @default.
• W2951764080 cites W2231266532 @default.
• W2951764080 cites W2244332295 @default.
• W2951764080 cites W2259076235 @default.
• W2951764080 cites W2484085504 @default.
• W2951764080 cites W2519683219 @default.
• W2951764080 cites W2519845840 @default.
• W2951764080 cites W2574737543 @default.
• W2951764080 cites W2581971523 @default.
• W2951764080 cites W2591707313 @default.
• W2951764080 cites W2738466971 @default.
• W2951764080 cites W2779724718 @default.
• W2951764080 cites W2790118715 @default.
• W2951764080 cites W2889631323 @default.
• W2951764080 cites W2909839835 @default.
• W2951764080 cites W4232558597 @default.
• W2951764080 doi "https://doi.org/10.1016/j.cub.2019.05.055" @default.
• W2951764080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31204161" @default.
• W2951764080 hasPublicationYear "2019" @default.
• W2951764080 type Work @default.

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