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- W2951832335 abstract "An efficient and general synthesis of aziridines by the reaction of imines derived from p-toluenesulfonamides with in situ generated iodomethyllithium, with a simple and rapid experimental protocol, is reported for the first time. The reaction with the chiral aldimine derived from phenylalaninal allowed access to (2R,1′S)-2-(1′-aminoalkyl)aziridine with very high diastereoselectivity, in enantiopure form. A mechanism to explain this novel reaction is proposed." @default.
- W2951832335 created "2019-06-27" @default.
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- W2951832335 date "2009-03-10" @default.
- W2951832335 modified "2023-10-18" @default.
- W2951832335 title "ChemInform Abstract: Addition Reactions of Iodomethyllithium to Imines. A Direct and Efficient Synthesis of Aziridines and Enantiopure Amino Aziridines." @default.
- W2951832335 cites W2116314207 @default.
- W2951832335 doi "https://doi.org/10.1002/chin.200910094" @default.
- W2951832335 hasPublicationYear "2009" @default.
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