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- W2951840306 abstract "Mesenchymal stem cells (MSCs) are pluripotent progenitor cells with the capabilities of self-renewing, differentiating into multiple lineages, and achieving trophic effects during tissue repair. MSCs can secrete extracellular vesicles (EVs) including exosomes and microvesicles, which mediate their trophic effects on other cells. Carrying a variety of intracellular molecules of MSCs including lipids, proteins, RNA (mRNA and noncoding RNA), and DNA, EVs deliver them into other cells to regulate tissue regeneration process. The therapeutic effects of MSC-derived EVs have been observed in a number of animal disease models. In this review, we focus on the current state and future directions of MSC-derived EVs in regenerative medicine. Anat Rec, 2019. © 2019 Wiley Periodicals, Inc." @default.
- W2951840306 created "2019-06-27" @default.
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- W2951840306 date "2019-06-17" @default.
- W2951840306 modified "2023-10-02" @default.
- W2951840306 title "Mesenchymal Stem Cell (MSC)‐Derived Extracellular Vesicles: Potential Therapeutics as MSC Trophic Mediators in Regenerative Medicine" @default.
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- W2951840306 doi "https://doi.org/10.1002/ar.24186" @default.
- W2951840306 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8327470" @default.
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