Matches in SemOpenAlex for { <https://semopenalex.org/work/W2951845265> ?p ?o ?g. }
- W2951845265 endingPage "294" @default.
- W2951845265 startingPage "288" @default.
- W2951845265 abstract "Abstract Aedes aegypti is associated with the transmission of numerous human and animal diseases, such as yellow fever, dengue fever, chikungunya, and more recently Zika virus. Emerging insecticide resistance has created a need to develop new mosquitocidal agents for effective control operations. A series of benzothiazole-piperidine derivatives ( 1-24 ) were investigated for their larvicidal and adulticidal effects on Ae. aegypti It was observed that compounds 2 , 4 , 6 , 7 , 8 , 11 and 13 showed notable larvicidal activity. Furthermore, compounds 6 and 10 showed promising adulticidal activity. Based on the mosquitocidal properties of these compounds, docking studies were also carried out in the active site of the Ae SCP2 enzyme to explore any insights into further in vitro enzyme studies. Docking results indicated that all these active compounds showed reasonable interactions with critical residues in the active site of this enzyme. This outcome suggested that these compounds might show their larvicidal and adulticidal effects via the inhibition of Ae SCP2. According to in vitro and in silico studies, compounds 2 , 4 , 6 , 7 , 8 , 10 , 11 and 13 stand out as candidates for further studies." @default.
- W2951845265 created "2019-06-27" @default.
- W2951845265 creator A5012420587 @default.
- W2951845265 creator A5018813584 @default.
- W2951845265 creator A5025767829 @default.
- W2951845265 creator A5040352588 @default.
- W2951845265 creator A5048968214 @default.
- W2951845265 creator A5064850975 @default.
- W2951845265 creator A5079486727 @default.
- W2951845265 date "2019-06-07" @default.
- W2951845265 modified "2023-10-12" @default.
- W2951845265 title "Biological evaluation of a series of benzothiazole derivatives as mosquitocidal agents" @default.
- W2951845265 cites W2021255861 @default.
- W2951845265 cites W2046461222 @default.
- W2951845265 cites W2088791119 @default.
- W2951845265 cites W2095300431 @default.
- W2951845265 cites W2098086227 @default.
- W2951845265 cites W2100576351 @default.
- W2951845265 cites W2114358906 @default.
- W2951845265 cites W2124449928 @default.
- W2951845265 cites W2131222241 @default.
- W2951845265 cites W2140464539 @default.
- W2951845265 cites W2149499629 @default.
- W2951845265 cites W2150460396 @default.
- W2951845265 cites W2153477946 @default.
- W2951845265 cites W2159008002 @default.
- W2951845265 cites W2162556586 @default.
- W2951845265 cites W2164612146 @default.
- W2951845265 cites W2165257089 @default.
- W2951845265 cites W2166537326 @default.
- W2951845265 cites W2217327291 @default.
- W2951845265 cites W2323962430 @default.
- W2951845265 cites W2482460018 @default.
- W2951845265 cites W2510879532 @default.
- W2951845265 cites W2593954251 @default.
- W2951845265 cites W2606167175 @default.
- W2951845265 cites W2737020048 @default.
- W2951845265 cites W2765839878 @default.
- W2951845265 cites W2952656992 @default.
- W2951845265 cites W427425070 @default.
- W2951845265 doi "https://doi.org/10.1515/chem-2019-0027" @default.
- W2951845265 hasPublicationYear "2019" @default.
- W2951845265 type Work @default.
- W2951845265 sameAs 2951845265 @default.
- W2951845265 citedByCount "11" @default.
- W2951845265 countsByYear W29518452652020 @default.
- W2951845265 countsByYear W29518452652021 @default.
- W2951845265 countsByYear W29518452652022 @default.
- W2951845265 countsByYear W29518452652023 @default.
- W2951845265 crossrefType "journal-article" @default.
- W2951845265 hasAuthorship W2951845265A5012420587 @default.
- W2951845265 hasAuthorship W2951845265A5018813584 @default.
- W2951845265 hasAuthorship W2951845265A5025767829 @default.
- W2951845265 hasAuthorship W2951845265A5040352588 @default.
- W2951845265 hasAuthorship W2951845265A5048968214 @default.
- W2951845265 hasAuthorship W2951845265A5064850975 @default.
- W2951845265 hasAuthorship W2951845265A5079486727 @default.
- W2951845265 hasBestOaLocation W29518452651 @default.
- W2951845265 hasConcept C104317684 @default.
- W2951845265 hasConcept C159047783 @default.
- W2951845265 hasConcept C173758957 @default.
- W2951845265 hasConcept C181199279 @default.
- W2951845265 hasConcept C185592680 @default.
- W2951845265 hasConcept C202751555 @default.
- W2951845265 hasConcept C2522874641 @default.
- W2951845265 hasConcept C2775905019 @default.
- W2951845265 hasConcept C2777053367 @default.
- W2951845265 hasConcept C2777456753 @default.
- W2951845265 hasConcept C2777775583 @default.
- W2951845265 hasConcept C2779635636 @default.
- W2951845265 hasConcept C2781273456 @default.
- W2951845265 hasConcept C41183919 @default.
- W2951845265 hasConcept C41685203 @default.
- W2951845265 hasConcept C42972112 @default.
- W2951845265 hasConcept C533803919 @default.
- W2951845265 hasConcept C55493867 @default.
- W2951845265 hasConcept C556039675 @default.
- W2951845265 hasConcept C59822182 @default.
- W2951845265 hasConcept C71924100 @default.
- W2951845265 hasConcept C86803240 @default.
- W2951845265 hasConcept C98274493 @default.
- W2951845265 hasConceptScore W2951845265C104317684 @default.
- W2951845265 hasConceptScore W2951845265C159047783 @default.
- W2951845265 hasConceptScore W2951845265C173758957 @default.
- W2951845265 hasConceptScore W2951845265C181199279 @default.
- W2951845265 hasConceptScore W2951845265C185592680 @default.
- W2951845265 hasConceptScore W2951845265C202751555 @default.
- W2951845265 hasConceptScore W2951845265C2522874641 @default.
- W2951845265 hasConceptScore W2951845265C2775905019 @default.
- W2951845265 hasConceptScore W2951845265C2777053367 @default.
- W2951845265 hasConceptScore W2951845265C2777456753 @default.
- W2951845265 hasConceptScore W2951845265C2777775583 @default.
- W2951845265 hasConceptScore W2951845265C2779635636 @default.
- W2951845265 hasConceptScore W2951845265C2781273456 @default.
- W2951845265 hasConceptScore W2951845265C41183919 @default.
- W2951845265 hasConceptScore W2951845265C41685203 @default.
- W2951845265 hasConceptScore W2951845265C42972112 @default.
- W2951845265 hasConceptScore W2951845265C533803919 @default.