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- W2951849204 abstract "The multistep continuous flow assembly of 2-(1<i>H</i>-indol-3-yl)thiazoles using a Syrris AFRICA<sup>®</sup> synthesis station is reported. Sequential Hantzsch thiazole synthesis, deketalization, and Fischer indole synthesis provides rapid and efficient access to highly functionalized, pharmacologically significant 2-(1<i>H</i>-indol-3-yl)thiazoles. These complex drug-like small molecules are generated in reaction times of less than 15 minutes and in high yields (38–82% over three chemical steps without isolation of intermediates)." @default.
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- W2951849204 date "2012-05-25" @default.
- W2951849204 modified "2023-10-18" @default.
- W2951849204 title "Automated Multistep Continuous Flow Synthesis of 2-(1H-Indol-3-yl)thiazole Derivatives" @default.
- W2951849204 doi "https://doi.org/10.1055/s-0031-1290953" @default.
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