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• W2951882034 abstract "SV-plaudit is a framework for rapidly curating structural variant (SV) predictions. For each SV, we generate an image that visualizes the coverage and alignment signals from a set of samples. Images are uploaded to our cloud framework where users assess the quality of each image using a client-side web application. Reports can then be generated as a tab-delimited file or annotated Variant Call Format (VCF) file. As a proof of principle, nine researchers collaborated for 1 hour to evaluate 1,350 SVs each. We anticipate that SV-plaudit will become a standard step in variant calling pipelines and the crowd-sourced curation of other biological results. Code available at https://github.com/jbelyeu/SV-plaudit Demonstration video available at https://www.youtube.com/watch?v=ono8kHMKxDs" @default.
• W2951882034 created "2019-06-27" @default.
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• W2951882034 date "2018-05-31" @default.
• W2951882034 modified "2023-10-15" @default.
• W2951882034 title "SV-plaudit: A cloud-based framework for manually curating thousands of structural variants" @default.
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• W2951882034 doi "https://doi.org/10.1093/gigascience/giy064" @default.
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