Matches in SemOpenAlex for { <https://semopenalex.org/work/W2951897480> ?p ?o ?g. }
- W2951897480 abstract "Abstract In spite of decades of linkage and association studies and its potential impact on human health, reliable prediction of an individual’s risk for heritable disease remains difficult. Large numbers of mapped loci do not explain substantial fractions of heritable variation, leaving an open question of whether accurate complex trait predictions can be achieved in practice. Here, we use a genome sequenced population of ∼7,000 yeast strains of high but varying relatedness, and predict growth traits from family information, effects of segregating genetic variants and growth in other environments with an average coefficient of determination R 2 of 0.91. This accuracy exceeds narrow-sense heritability, approaches limits imposed by measurement repeatability and is higher than achieved with a single assay in the laboratory. Our results prove that very accurate prediction of complex traits is possible, and suggest that additional data from families rather than reference cohorts may be more useful for this purpose." @default.
- W2951897480 created "2019-06-27" @default.
- W2951897480 creator A5029927126 @default.
- W2951897480 creator A5062738925 @default.
- W2951897480 creator A5063706428 @default.
- W2951897480 creator A5070566112 @default.
- W2951897480 creator A5084279149 @default.
- W2951897480 date "2016-05-10" @default.
- W2951897480 modified "2023-09-27" @default.
- W2951897480 title "Predicting quantitative traits from genome and phenome with near perfect accuracy" @default.
- W2951897480 cites W1780328778 @default.
- W2951897480 cites W1844405070 @default.
- W2951897480 cites W1967419464 @default.
- W2951897480 cites W1970964234 @default.
- W2951897480 cites W1973022936 @default.
- W2951897480 cites W1980991473 @default.
- W2951897480 cites W1983539381 @default.
- W2951897480 cites W1992140675 @default.
- W2951897480 cites W1993849688 @default.
- W2951897480 cites W1997338841 @default.
- W2951897480 cites W2007346133 @default.
- W2951897480 cites W2009467402 @default.
- W2951897480 cites W2023455695 @default.
- W2951897480 cites W2039013541 @default.
- W2951897480 cites W2039279598 @default.
- W2951897480 cites W2048011602 @default.
- W2951897480 cites W2053674619 @default.
- W2951897480 cites W2054885243 @default.
- W2951897480 cites W2063661977 @default.
- W2951897480 cites W2085164119 @default.
- W2951897480 cites W2102373440 @default.
- W2951897480 cites W2114044285 @default.
- W2951897480 cites W2127072693 @default.
- W2951897480 cites W2128343509 @default.
- W2951897480 cites W2128416240 @default.
- W2951897480 cites W2133102806 @default.
- W2951897480 cites W2145325541 @default.
- W2951897480 cites W2146806489 @default.
- W2951897480 cites W2155992983 @default.
- W2951897480 cites W2163924952 @default.
- W2951897480 cites W2171679524 @default.
- W2951897480 cites W2188707104 @default.
- W2951897480 cites W2253315254 @default.
- W2951897480 cites W2263825730 @default.
- W2951897480 cites W2345359545 @default.
- W2951897480 cites W2478172081 @default.
- W2951897480 cites W2949625879 @default.
- W2951897480 cites W2952887669 @default.
- W2951897480 doi "https://doi.org/10.1038/ncomms11512" @default.
- W2951897480 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4866306" @default.
- W2951897480 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27160605" @default.
- W2951897480 hasPublicationYear "2016" @default.
- W2951897480 type Work @default.
- W2951897480 sameAs 2951897480 @default.
- W2951897480 citedByCount "32" @default.
- W2951897480 countsByYear W29518974802016 @default.
- W2951897480 countsByYear W29518974802017 @default.
- W2951897480 countsByYear W29518974802018 @default.
- W2951897480 countsByYear W29518974802019 @default.
- W2951897480 countsByYear W29518974802020 @default.
- W2951897480 countsByYear W29518974802021 @default.
- W2951897480 countsByYear W29518974802022 @default.
- W2951897480 countsByYear W29518974802023 @default.
- W2951897480 crossrefType "journal-article" @default.
- W2951897480 hasAuthorship W2951897480A5029927126 @default.
- W2951897480 hasAuthorship W2951897480A5062738925 @default.
- W2951897480 hasAuthorship W2951897480A5063706428 @default.
- W2951897480 hasAuthorship W2951897480A5070566112 @default.
- W2951897480 hasAuthorship W2951897480A5084279149 @default.
- W2951897480 hasBestOaLocation W29518974801 @default.
- W2951897480 hasConcept C104317684 @default.
- W2951897480 hasConcept C106208931 @default.
- W2951897480 hasConcept C106934330 @default.
- W2951897480 hasConcept C135763542 @default.
- W2951897480 hasConcept C141231307 @default.
- W2951897480 hasConcept C144621757 @default.
- W2951897480 hasConcept C153209595 @default.
- W2951897480 hasConcept C161890455 @default.
- W2951897480 hasConcept C186413461 @default.
- W2951897480 hasConcept C199360897 @default.
- W2951897480 hasConcept C2908647359 @default.
- W2951897480 hasConcept C2993967602 @default.
- W2951897480 hasConcept C31266012 @default.
- W2951897480 hasConcept C41008148 @default.
- W2951897480 hasConcept C54355233 @default.
- W2951897480 hasConcept C70721500 @default.
- W2951897480 hasConcept C71924100 @default.
- W2951897480 hasConcept C78458016 @default.
- W2951897480 hasConcept C7952369 @default.
- W2951897480 hasConcept C81941488 @default.
- W2951897480 hasConcept C86803240 @default.
- W2951897480 hasConcept C9287583 @default.
- W2951897480 hasConcept C99454951 @default.
- W2951897480 hasConceptScore W2951897480C104317684 @default.
- W2951897480 hasConceptScore W2951897480C106208931 @default.
- W2951897480 hasConceptScore W2951897480C106934330 @default.
- W2951897480 hasConceptScore W2951897480C135763542 @default.
- W2951897480 hasConceptScore W2951897480C141231307 @default.
- W2951897480 hasConceptScore W2951897480C144621757 @default.
- W2951897480 hasConceptScore W2951897480C153209595 @default.