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- W2951904847 abstract "Heterocycles with potential bioactive properties are of greater interest to researchers engaged in the areas of natural product synthesis and heterocyclic methodology. Several FDA (Food and Drug Administration) approved pharmaceutical drugs incorporate a heterocyclic motif in their core structure. Spiroisoxazolines and spiropyrazolines belong to the class of five membered heterocycles that have received greater attention over the past four decades. Spiropyrazolines structurally resemble naturally occurring spiroisoxazolines, have extra nitrogen in place of isoxazoline oxygen, and offer the viability to construct useful analogs for the exploration of possible bioactivity. As of today, no reports on the construction of these spiropyrazolines were available and the current review is aimed at providing a comprehensive discussion of the protocols applied in the synthesis of functionalized spiropyrazolines." @default.
- W2951904847 created "2019-06-27" @default.
- W2951904847 creator A5028446168 @default.
- W2951904847 date "2013-08-08" @default.
- W2951904847 modified "2023-09-27" @default.
- W2951904847 title "ChemInform Abstract: Cycloadditions and Condensations as Essential Tools in Spiropyrazoline Synthesis" @default.
- W2951904847 cites W2071713557 @default.
- W2951904847 doi "https://doi.org/10.1002/chin.201335223" @default.
- W2951904847 hasPublicationYear "2013" @default.
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