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- W2951949002 abstract "Several monoacylated alkylene diamines have been obtained in the reaction of appropriate amine with methyl phenylacetate or ethyl formate. The mono protected diamines were used as alkylating agents in reactions with l-(2,4-dinitrophenyl)-5-nitrouracil. The series of hitherto unknown 1-(ω-aminoalkyl)-5-nitrouracil derivatives have been obtained as a result of the uracil ring transformation. The best yield of 1-(ω-aminoalkyl)-5-nitro-uracils was obtained when N-Boc protected alkylene diamines were applied in this reaction. The N-Boc protecting group was cleaved using diluted trifluoroacetic acid, and the liberated amines were subjected to reaction with phthalic anhydride and naphthalene 1,8-dicarboxylic anhydride." @default.
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- W2951949002 date "2009-01-01" @default.
- W2951949002 modified "2023-09-24" @default.
- W2951949002 title "A Convenient Synthesis of 1-(omega-Aminoalkyl)-5-nitro-1H-pyrimidine-2,4-diones" @default.
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