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- W2951962913 abstract "Enantioselective preparation of C2-symmetric (−)-(2S,5S)-N-benzyl-trans-2,5-bis(acetoxymethyl)pyrrolidine was carried out by the lipase-catalyzed hydrolysis of racemic diacetate. Organic co-solvent affected the enantioselectivity and 50% DMSO in the phosphate buffer was found to be the optimal solvent system. A possible active site model was also described." @default.
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- W2951962913 date "1996-01-01" @default.
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- W2951962913 title "Lipase-catalyzed kinetic resolution of trans-2,5-disubstituted pyrrolidine derivatives" @default.
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- W2951962913 doi "https://doi.org/10.1016/0040-4020(95)00907-8" @default.
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