Matches in SemOpenAlex for { <https://semopenalex.org/work/W2951963565> ?p ?o ?g. }
- W2951963565 endingPage "e87" @default.
- W2951963565 startingPage "e79" @default.
- W2951963565 abstract "ABSTRACT Background and Aims: The aim of the study was to aid decisions on prognosis and transplantation; this study describes the outcome of children with intestinal failure managed by the multidisciplinary intestinal rehabilitation program at the Royal Children's Hospital, Melbourne. Methods: Retrospective review of children requiring parenteral nutrition (PN) for >3 months who were assessed for home PN between 1991 and 2011. Results: A total of 51 children were included. Forty-two (82%) had short bowel syndrome (SBS), 5 (10%) had chronic intestinal pseudo-obstruction syndrome, and 4 (8%) had congenital enteropathies. Median small bowel length for patients with SBS was 45 cm (interquartile range 30–80) or 23.9% of the expected length for age (interquartile range 17.0%–40.6%). Overall survival rate was 84% (43/51). Mortality in children (n = 7) occurred after a median of 13.2 months (range 6.2–29.2) with intestinal failure–associated liver disease (IFALD) being the only predictor ( P = 0.001). Out of 50 children 21 (42%) had IFALD. Children who were premature ( P = 0.013), had SBS ( P = 0.038), and/or frequent sepsis ( P = 0.014) were more likely to develop IFALD. PN weaning occurred in 27 of 35 (77%) SBS survivors, after a median of 10.8 months (up to 8.2 years), with longer residual small bowel ( P = 0.025), preservation of the ileocecal valve ( P = 0.013) and colon ( P = 0.011) being predictors. None of 5 (0%) patients with chronic intestinal pseudo-obstruction syndrome and 2 of 4 (50%) patients with congenital enteropathies weaned off PN. Overall sepsis rate was 7.3 episodes/1000 line days. Frequency of sepsis and longevity of central lines improved with time as patients grew older (both P < 0.001). Conclusions: Long-term PN with intestinal rehabilitation was effective in treating most children with intestinal failure. Children with severe refractory IFALD may have benefited from intestinal transplantation." @default.
- W2951963565 created "2019-06-27" @default.
- W2951963565 creator A5007425462 @default.
- W2951963565 creator A5010976699 @default.
- W2951963565 creator A5012940304 @default.
- W2951963565 creator A5040462138 @default.
- W2951963565 creator A5046014101 @default.
- W2951963565 creator A5062610937 @default.
- W2951963565 creator A5071307888 @default.
- W2951963565 creator A5073739368 @default.
- W2951963565 date "2019-09-01" @default.
- W2951963565 modified "2023-10-10" @default.
- W2951963565 title "Outcomes of Children With Chronic Intestinal Failure: Experience Over 2 Decades at a Tertiary Paediatric Hospital" @default.
- W2951963565 cites W1735764346 @default.
- W2951963565 cites W1777382430 @default.
- W2951963565 cites W1935077335 @default.
- W2951963565 cites W1950100204 @default.
- W2951963565 cites W1966676383 @default.
- W2951963565 cites W1967066877 @default.
- W2951963565 cites W1983046015 @default.
- W2951963565 cites W1984784375 @default.
- W2951963565 cites W1992557035 @default.
- W2951963565 cites W2004535814 @default.
- W2951963565 cites W2009691083 @default.
- W2951963565 cites W2017020957 @default.
- W2951963565 cites W2020447949 @default.
- W2951963565 cites W2022105501 @default.
- W2951963565 cites W2023994289 @default.
- W2951963565 cites W2033126092 @default.
- W2951963565 cites W2046446338 @default.
- W2951963565 cites W2062294512 @default.
- W2951963565 cites W2067817547 @default.
- W2951963565 cites W2072092609 @default.
- W2951963565 cites W2072676789 @default.
- W2951963565 cites W2086605988 @default.
- W2951963565 cites W2095063281 @default.
- W2951963565 cites W2098919774 @default.
- W2951963565 cites W2104964844 @default.
- W2951963565 cites W2111884535 @default.
- W2951963565 cites W2117582658 @default.
- W2951963565 cites W2122580890 @default.
- W2951963565 cites W2123014937 @default.
- W2951963565 cites W2154472085 @default.
- W2951963565 cites W2165911612 @default.
- W2951963565 cites W2172205164 @default.
- W2951963565 cites W2301439855 @default.
- W2951963565 cites W2568335412 @default.
- W2951963565 cites W2591847570 @default.
- W2951963565 cites W2765607287 @default.
- W2951963565 cites W2792137877 @default.
- W2951963565 cites W2915975234 @default.
- W2951963565 doi "https://doi.org/10.1097/mpg.0000000000002384" @default.
- W2951963565 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31169663" @default.
- W2951963565 hasPublicationYear "2019" @default.
- W2951963565 type Work @default.
- W2951963565 sameAs 2951963565 @default.
- W2951963565 citedByCount "14" @default.
- W2951963565 countsByYear W29519635652020 @default.
- W2951963565 countsByYear W29519635652021 @default.
- W2951963565 countsByYear W29519635652022 @default.
- W2951963565 countsByYear W29519635652023 @default.
- W2951963565 crossrefType "journal-article" @default.
- W2951963565 hasAuthorship W2951963565A5007425462 @default.
- W2951963565 hasAuthorship W2951963565A5010976699 @default.
- W2951963565 hasAuthorship W2951963565A5012940304 @default.
- W2951963565 hasAuthorship W2951963565A5040462138 @default.
- W2951963565 hasAuthorship W2951963565A5046014101 @default.
- W2951963565 hasAuthorship W2951963565A5062610937 @default.
- W2951963565 hasAuthorship W2951963565A5071307888 @default.
- W2951963565 hasAuthorship W2951963565A5073739368 @default.
- W2951963565 hasBestOaLocation W29519635651 @default.
- W2951963565 hasConcept C119060515 @default.
- W2951963565 hasConcept C126322002 @default.
- W2951963565 hasConcept C141071460 @default.
- W2951963565 hasConcept C167135981 @default.
- W2951963565 hasConcept C187212893 @default.
- W2951963565 hasConcept C2777226302 @default.
- W2951963565 hasConcept C2778384902 @default.
- W2951963565 hasConcept C2779621457 @default.
- W2951963565 hasConcept C2779820108 @default.
- W2951963565 hasConcept C2911091166 @default.
- W2951963565 hasConcept C3018696549 @default.
- W2951963565 hasConcept C71924100 @default.
- W2951963565 hasConcept C78722104 @default.
- W2951963565 hasConcept C90924648 @default.
- W2951963565 hasConceptScore W2951963565C119060515 @default.
- W2951963565 hasConceptScore W2951963565C126322002 @default.
- W2951963565 hasConceptScore W2951963565C141071460 @default.
- W2951963565 hasConceptScore W2951963565C167135981 @default.
- W2951963565 hasConceptScore W2951963565C187212893 @default.
- W2951963565 hasConceptScore W2951963565C2777226302 @default.
- W2951963565 hasConceptScore W2951963565C2778384902 @default.
- W2951963565 hasConceptScore W2951963565C2779621457 @default.
- W2951963565 hasConceptScore W2951963565C2779820108 @default.
- W2951963565 hasConceptScore W2951963565C2911091166 @default.
- W2951963565 hasConceptScore W2951963565C3018696549 @default.
- W2951963565 hasConceptScore W2951963565C71924100 @default.
- W2951963565 hasConceptScore W2951963565C78722104 @default.