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- W2951976543 abstract "Metal-free, p-toluenesulfonic acid (p-TSA)-mediated, straightforward propargylation of β-ketothioamides with aryl propargyl alcohol has been achieved at room temperature. In addition, the reaction also provided thiazole rings as byproducts. Furthermore, the propargylated thioamides undergo intramolecular 1,5-cyclization to afford fully substituted (hydro)thiophenes in the presence of base. Notably, the approach is pot, atom, and step economical (PASE)." @default.
- W2951976543 created "2019-06-27" @default.
- W2951976543 creator A5048533063 @default.
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- W2951976543 date "2016-11-01" @default.
- W2951976543 modified "2023-09-27" @default.
- W2951976543 title "ChemInform Abstract: P-TSA/Base-Promoted Propargylation/Cyclization of β-Ketothioamides for the Regioselective Synthesis of Highly Substituted (Hydro)thiophenes." @default.
- W2951976543 cites W2473094671 @default.
- W2951976543 doi "https://doi.org/10.1002/chin.201648115" @default.
- W2951976543 hasPublicationYear "2016" @default.
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