FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2951988194> ?p ?o ?g. }

• W2951988194 endingPage "253" @default.
• W2951988194 startingPage "246" @default.
• W2951988194 abstract "Calcium (Ca2+) dysregulation is a major catalytic event. Ca2+ dysregulation leads to neuronal cell death and brain damage result in cerebral ischemia. Neurons are unable in maintaining calcium homeostasis. Ca2+ homeostasis imbalance results in increased calcium influx and impaired calcium extrusion across the plasma membrane. Ca2+ dysregulation is mediated by different cellular and biochemical mechanism, which leads to neuronal loss resulting stroke/cerebral ischemia. A better understanding of the Ca2+ dysregulation might help in the development of new treatments in order to reduce ischemic brain injury. An optimal concentration of Ca2+ does not lead to neurotoxicity in the ischemic neuron. Intracellular Ca2+ act as a trigger for acute neurotoxicity and this cause induction of long-lasting processes leading to necrotic and/or apoptotic post-ischemic delayed neuronal death or of compensatory, neuroprotective mechanisms has increased considerably. Moreover, routes of ischemic Ca2+ influx to neurons, involvement of intracellular Ca2+ stores and Ca2+ buffers, spatial and temporal relations between ischemia-induced increases in intracellular Ca2+ concentration and neurotoxicity will further increase our understanding about underlying mechanism and they can act as a target for the development of drugs. Here, in our article we are trying to provide a brief overview of various Ca2+ influx pathways involve in ischemic neuron and how ischemic neuron attempts to counterbalance this calcium overload." @default.
• W2951988194 created "2019-06-27" @default.
• W2951988194 creator A5012858541 @default.
• W2951988194 creator A5017707305 @default.
• W2951988194 creator A5022336581 @default.
• W2951988194 creator A5056191529 @default.
• W2951988194 creator A5070092804 @default.
• W2951988194 date "2019-06-20" @default.
• W2951988194 modified "2023-10-04" @default.
• W2951988194 title "Modes of Calcium Regulation in Ischemic Neuron" @default.
• W2951988194 cites W1963775318 @default.
• W2951988194 cites W1968177047 @default.
• W2951988194 cites W1971944962 @default.
• W2951988194 cites W1977584840 @default.
• W2951988194 cites W1992113221 @default.
• W2951988194 cites W1995965039 @default.
• W2951988194 cites W2010204822 @default.
• W2951988194 cites W2023392970 @default.
• W2951988194 cites W2044806678 @default.
• W2951988194 cites W2057104241 @default.
• W2951988194 cites W2060927474 @default.
• W2951988194 cites W2073585436 @default.
• W2951988194 cites W2078621964 @default.
• W2951988194 cites W2083003235 @default.
• W2951988194 cites W2141722155 @default.
• W2951988194 cites W2155351497 @default.
• W2951988194 cites W2166002527 @default.
• W2951988194 cites W2260748729 @default.
• W2951988194 cites W2307390251 @default.
• W2951988194 cites W2520965644 @default.
• W2951988194 cites W2549985930 @default.
• W2951988194 cites W2589836520 @default.
• W2951988194 cites W2775474332 @default.
• W2951988194 cites W2776668311 @default.
• W2951988194 cites W2777541397 @default.
• W2951988194 cites W2790773368 @default.
• W2951988194 cites W2791166857 @default.
• W2951988194 cites W2792702377 @default.
• W2951988194 cites W2795560018 @default.
• W2951988194 cites W2801666323 @default.
• W2951988194 cites W2805040381 @default.
• W2951988194 cites W2809091331 @default.
• W2951988194 cites W2810895131 @default.
• W2951988194 cites W2888791810 @default.
• W2951988194 cites W2891892218 @default.
• W2951988194 cites W2892032828 @default.
• W2951988194 cites W2897902608 @default.
• W2951988194 cites W2898927772 @default.
• W2951988194 cites W2902890940 @default.
• W2951988194 cites W2905371686 @default.
• W2951988194 cites W2906664311 @default.
• W2951988194 cites W2911864747 @default.
• W2951988194 cites W2913920467 @default.
• W2951988194 cites W2921289538 @default.
• W2951988194 cites W2922383116 @default.
• W2951988194 cites W2941818042 @default.
• W2951988194 cites W2946013240 @default.
• W2951988194 doi "https://doi.org/10.1007/s12291-019-00838-9" @default.
• W2951988194 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6660593" @default.
• W2951988194 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31391713" @default.
• W2951988194 hasPublicationYear "2019" @default.
• W2951988194 type Work @default.
• W2951988194 sameAs 2951988194 @default.
• W2951988194 citedByCount "22" @default.
• W2951988194 countsByYear W29519881942020 @default.
• W2951988194 countsByYear W29519881942021 @default.
• W2951988194 countsByYear W29519881942022 @default.
• W2951988194 countsByYear W29519881942023 @default.
• W2951988194 crossrefType "journal-article" @default.
• W2951988194 hasAuthorship W2951988194A5012858541 @default.
• W2951988194 hasAuthorship W2951988194A5017707305 @default.
• W2951988194 hasAuthorship W2951988194A5022336581 @default.
• W2951988194 hasAuthorship W2951988194A5056191529 @default.
• W2951988194 hasAuthorship W2951988194A5070092804 @default.
• W2951988194 hasBestOaLocation W29519881942 @default.
• W2951988194 hasConcept C126322002 @default.
• W2951988194 hasConcept C169760540 @default.
• W2951988194 hasConcept C181080969 @default.
• W2951988194 hasConcept C185592680 @default.
• W2951988194 hasConcept C190283241 @default.
• W2951988194 hasConcept C25498285 @default.
• W2951988194 hasConcept C2778794669 @default.
• W2951988194 hasConcept C2779491297 @default.
• W2951988194 hasConcept C29730261 @default.
• W2951988194 hasConcept C31573885 @default.
• W2951988194 hasConcept C519063684 @default.
• W2951988194 hasConcept C541997718 @default.
• W2951988194 hasConcept C55493867 @default.
• W2951988194 hasConcept C63645605 @default.
• W2951988194 hasConcept C71924100 @default.
• W2951988194 hasConcept C79879829 @default.
• W2951988194 hasConcept C86803240 @default.
• W2951988194 hasConcept C87975464 @default.
• W2951988194 hasConcept C95444343 @default.
• W2951988194 hasConceptScore W2951988194C126322002 @default.
• W2951988194 hasConceptScore W2951988194C169760540 @default.
• W2951988194 hasConceptScore W2951988194C181080969 @default.
• W2951988194 hasConceptScore W2951988194C185592680 @default.

• next