Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952069128> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2952069128 abstract "Infectious diseases, particularly those due to multi-drug resistant bacterial strains are almost impossible to cure globally. In this study we investigated the inhibitory effects of Azadirachta indica A. Juss secondary metabolites (AISM) formulated soap and cream for management of infectious and oxidative stress-related diseases (OSD).The antibacterial, radical scavenging and cytotoxic effects of the neem cosmetics were examined by serial dilution, spectrophotometric and hemolytic techniques respectively, while the AISM in the essential oils (EOs) were elucidated by Gas chromatography-mass spectrometry (GC-MS) and retention index.The neem cosmetics without AISM exhibited bacteriostatic effects against five reference bacterial strains (Staphylococcus aureus, Listeria ivanovii, Enterobacter cloacae, Mycobacterium smegmatis, and Streptococcus uberis) and two confirmed multi-drug resistant bacterial strains (Vibrio paraheamolyticues, Escherichia coli 180) at 0.80 mg/mL. Conversely, at less than 0.50 mg/mL the neem soap produced with AISM demonstrated bactericidal effects against most of these test pathogens linked to infectious diseases. The neem soap containing AISMs displayed noteworthy effects in scavenging radicals associated with OSD at < 1.76 mg/mL. The cosmetics were not toxic to human red blood cells below 0.70 mg/ mL. To our known, the AISM predominantly caryophyllene (30.02%), phytol (14.12%), elemene (13.40%) and linoleic acid (10.5%) exceptional inhibitory effects in neem cosmetics are reported here for the first time.The study indicates that apart from traditional uses of A. indica, the EO contained potent bioactive AISM and feasible as an antimicrobial agent, an alternative to synthetic antioxidant, likewise considered novel in the pharmaceutical, cosmetics industries and as food preservatives." @default.
- W2952069128 created "2019-06-27" @default.
- W2952069128 creator A5007777756 @default.
- W2952069128 creator A5021429705 @default.
- W2952069128 creator A5084731090 @default.
- W2952069128 date "2019-06-10" @default.
- W2952069128 modified "2023-09-24" @default.
- W2952069128 title "Inhibitory effects of Azadirachta indica secondary metabolites formulated cosmetics on some infectious pathogens and oxidative stress radicals" @default.
- W2952069128 cites W1914441344 @default.
- W2952069128 cites W1968507863 @default.
- W2952069128 cites W1971757550 @default.
- W2952069128 cites W1981307220 @default.
- W2952069128 cites W1986855364 @default.
- W2952069128 cites W1998321859 @default.
- W2952069128 cites W2007970780 @default.
- W2952069128 cites W2023418017 @default.
- W2952069128 cites W2025034007 @default.
- W2952069128 cites W2035553005 @default.
- W2952069128 cites W2041637307 @default.
- W2952069128 cites W2047489741 @default.
- W2952069128 cites W2055050250 @default.
- W2952069128 cites W2060786754 @default.
- W2952069128 cites W2078248663 @default.
- W2952069128 cites W2094259958 @default.
- W2952069128 cites W2098504997 @default.
- W2952069128 cites W2105402817 @default.
- W2952069128 cites W2119518831 @default.
- W2952069128 cites W2145012282 @default.
- W2952069128 cites W2156437431 @default.
- W2952069128 cites W2159017944 @default.
- W2952069128 cites W2168429897 @default.
- W2952069128 cites W2232738866 @default.
- W2952069128 cites W2275102609 @default.
- W2952069128 cites W2306291768 @default.
- W2952069128 cites W2312777693 @default.
- W2952069128 cites W2471644962 @default.
- W2952069128 cites W2559438100 @default.
- W2952069128 cites W2730198268 @default.
- W2952069128 cites W4251223925 @default.
- W2952069128 cites W776515368 @default.
- W2952069128 doi "https://doi.org/10.1186/s12906-019-2538-0" @default.
- W2952069128 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6558881" @default.
- W2952069128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31182095" @default.
- W2952069128 hasPublicationYear "2019" @default.
- W2952069128 type Work @default.
- W2952069128 sameAs 2952069128 @default.
- W2952069128 citedByCount "4" @default.
- W2952069128 countsByYear W29520691282021 @default.
- W2952069128 countsByYear W29520691282022 @default.
- W2952069128 crossrefType "journal-article" @default.
- W2952069128 hasAuthorship W2952069128A5007777756 @default.
- W2952069128 hasAuthorship W2952069128A5021429705 @default.
- W2952069128 hasAuthorship W2952069128A5084731090 @default.
- W2952069128 hasBestOaLocation W29520691281 @default.
- W2952069128 hasConcept C185592680 @default.
- W2952069128 hasConcept C2779489039 @default.
- W2952069128 hasConcept C2781035296 @default.
- W2952069128 hasConcept C4937899 @default.
- W2952069128 hasConcept C523546767 @default.
- W2952069128 hasConcept C54355233 @default.
- W2952069128 hasConcept C556039675 @default.
- W2952069128 hasConcept C71924100 @default.
- W2952069128 hasConcept C86803240 @default.
- W2952069128 hasConcept C89423630 @default.
- W2952069128 hasConceptScore W2952069128C185592680 @default.
- W2952069128 hasConceptScore W2952069128C2779489039 @default.
- W2952069128 hasConceptScore W2952069128C2781035296 @default.
- W2952069128 hasConceptScore W2952069128C4937899 @default.
- W2952069128 hasConceptScore W2952069128C523546767 @default.
- W2952069128 hasConceptScore W2952069128C54355233 @default.
- W2952069128 hasConceptScore W2952069128C556039675 @default.
- W2952069128 hasConceptScore W2952069128C71924100 @default.
- W2952069128 hasConceptScore W2952069128C86803240 @default.
- W2952069128 hasConceptScore W2952069128C89423630 @default.
- W2952069128 hasIssue "1" @default.
- W2952069128 hasLocation W29520691281 @default.
- W2952069128 hasLocation W29520691282 @default.
- W2952069128 hasLocation W29520691283 @default.
- W2952069128 hasOpenAccess W2952069128 @default.
- W2952069128 hasPrimaryLocation W29520691281 @default.
- W2952069128 hasRelatedWork W1653766406 @default.
- W2952069128 hasRelatedWork W2077389111 @default.
- W2952069128 hasRelatedWork W2753184995 @default.
- W2952069128 hasRelatedWork W2900942887 @default.
- W2952069128 hasRelatedWork W2954159082 @default.
- W2952069128 hasRelatedWork W2980903890 @default.
- W2952069128 hasRelatedWork W2985891204 @default.
- W2952069128 hasRelatedWork W3038027106 @default.
- W2952069128 hasRelatedWork W2595375273 @default.
- W2952069128 hasRelatedWork W2894777053 @default.
- W2952069128 hasVolume "19" @default.
- W2952069128 isParatext "false" @default.
- W2952069128 isRetracted "false" @default.
- W2952069128 magId "2952069128" @default.
- W2952069128 workType "article" @default.