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- W2952080863 abstract "Optical coherence tomography (OCT) allowslabel-free, three-dimensional imaging of tissue structure. Currentimplementations of OCT can either image over long depth ranges atslow imaging speeds, or over limited depth ranges at high speeds.Here, we describe a new OCT paradigm that supports simultaneoushigh speed and long depth range imaging through subsamplingbandwidth compression. We show that this requires replacing theconventional wavelength-swept OCT laser source with awavelength-stepped laser. First we validated this concept bymodifying a slow, conventional wavelength-swept source with anintra-cavity Fabry-Perot etalon to provide a wavelength-steppedoutput. Using this source in an existing OCT system, we show thatwe can passively compress signals across a large depth range into alimited RF bandwidth. Next, to demonstrate high-speed opticaldomain subsampled imaging, we developed a novel wavelength-steppedlaser source based on intra-cavity pulse compression/stretching;this source provided an A-line rate of ~19 MHz. We then built apolarization-based quadrature interferometer to remove imagingartifacts induced by subsampling and comple-conjugate ambiguity. Acalibration and error compensation method was developed to fullyremove residual artifacts in the image. We combined the high speedlaser and the interferometer to demonstrate the first OCTcamera-like imaging across several centimeters of depth range. Theoptically subsampled OCT technology developed in this work mayoffer a new three-dimensional camera platform for endoscopic andintraoperative imaging applications." @default.
- W2952080863 created "2019-06-27" @default.
- W2952080863 creator A5033182955 @default.
- W2952080863 date "2015-01-01" @default.
- W2952080863 modified "2023-09-23" @default.
- W2952080863 title "Development of a three-dimensional camera based onsubsampled optical coherence tomography (OCT); Development of a 3-dimensional camera based onsubsampled optical coherence tomography (OCT); Development of a 3-D camera based on subsampled opticalcoherence tomography (OCT)" @default.
- W2952080863 hasPublicationYear "2015" @default.
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