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- W2952204482 abstract "A nickel-catalyzed cycloaddition of aromatic (O-benzyl)ketoximes with alkynes to afford 3,4-disubstituted isoquinoline derivatives has been developed. The reaction involves oxidative addition of N–O bond of O-benzylketoxime to Ni(0) and subsequent intermolecular C–H bond activation via elimination of benzyl alcohol. It was also found that ketoximes participate in the nickel-catalyzed reaction with alkynes to furnish isoquinoline N-oxide derivatives." @default.
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- W2952204482 date "2011-10-05" @default.
- W2952204482 modified "2023-10-16" @default.
- W2952204482 title "Nickel-catalyzed Cycloaddition of Aromatic (<i>O</i>-Benzyl)ketoximes with Alkynes to Produce Isoquinoline and Isoquinoline<i>N</i>-Oxide Derivatives" @default.
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- W2952204482 doi "https://doi.org/10.1246/cl.2011.1140" @default.
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