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- W2952302561 abstract "Fifteen heterocyclic phospho nate derivatives and their starting compounds have been evaluated in vitro for antibacterial and antifungal activities against standard strains: Enterococcus faecalis (A TCC 29212), Staphylococcus aureus (ATCC 2921)), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 2785 3) and yeast-like fungi ; Candida albicans and Candida tropicalis. The compounds newly synthesised have been identified by IH-NMR,.FT-IR and micro analysis . Among the tested compounds 12, 13, 16, 17, 18, 22 and 23 are found effective to inhibit the growth of Candida albicans and Candida tropicalis at the MICs between 100-800 Ilg/mL. The compounds tested here generally do not exhibit considerable antibacterial activity at the concentratiolJ studied (100-800 Ilg/mL), except compound 18 which exhibits antibacterial activity against gram-positive bacteria at the MIC of 400 Ilg/mL." @default.
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- W2952302561 date "1999-02-01" @default.
- W2952302561 modified "2023-10-18" @default.
- W2952302561 title "Synthesis of some heterocyclic phosphonates and their antibacterial and antifungal activities" @default.
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