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- W2952306743 abstract "A two step procedure for the regioselective synthesis of 3-substituted-2-aminoimidazo[1,2-a]pyrimidines is described. The key step is a Dimroth rearrangement of a mixture of 2 and 3-substituted aminoimidazo[1,2-a]pyrimidines that yields quantitatively one regioisomer. Reaction screening for the rearrangement step is reported. A multicomponent isocyanide based reaction is chosen as the preferred way for the synthesis of the precursors. Elucidation of regiochemistry has been done by X-ray determination of some representative compounds." @default.
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- W2952306743 date "2007-03-01" @default.
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- W2952306743 title "Regioselective two step synthesis of 3-substituted 2-aminoimidazo[1,2-a]pyrimidines" @default.
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- W2952306743 doi "https://doi.org/10.1016/j.tetlet.2006.11.181" @default.
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