Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952316204> ?p ?o ?g. }
- W2952316204 endingPage "871" @default.
- W2952316204 startingPage "864" @default.
- W2952316204 abstract "Background: The T-cell immunoglobulin and mucin domain 4 gene (TIMD4) rs6882076 single nucleotide polymorphism (SNP) has been associated with serum total cholesterol, low-density lipoprotein cholesterol and triglycerides (TG) levels, but the results are inconsistent. Moreover, little is known about such association in Chinese populations. The aim of this study was to detect the association of the TIMD4 rs6882076 SNP and serum lipid levels and the risk of coronary heart disease (CHD) and ischemic stroke (IS) in a Southern Chinese Han population. Methods: Genotypes of the TIMD4 rs6882076 SNP in 1765 unrelated subjects (CHD, 581; IS, 559 and healthy controls, 625) were determined by the Snapshot Technology. Results: The genotypic and allelic frequencies of the TIMD4 rs6882076 SNP were different between the CHD/IS patients and controls (P < 0.05 for all). The subjects with CT/TT genotypes were associated with decreased risk of CHD (P = 0.014 for CT/TT vs. CC genotypes, P = 0.010 for T vs. C alleles) and IS (P = 0.003 for CT/TT vs. CC genotypes; P = 0.016 for T vs. C alleles). The T allele carriers in healthy controls were also associated with decreased levels of serum TG. Conclusions: The results of the present study suggest that the TIMD4 rs6882076 SNP is associated with decreased risk of CHD and IS in our study population. It is likely to decrease the CHD and IS risk by reducing serum TG levels." @default.
- W2952316204 created "2019-06-27" @default.
- W2952316204 creator A5014672450 @default.
- W2952316204 creator A5048457452 @default.
- W2952316204 creator A5068327668 @default.
- W2952316204 creator A5068795845 @default.
- W2952316204 creator A5069913517 @default.
- W2952316204 creator A5071951923 @default.
- W2952316204 date "2019-01-01" @default.
- W2952316204 modified "2023-10-15" @default.
- W2952316204 title "TIMD4 rs6882076 SNP Is Associated with Decreased Levels of Triglycerides and the Risk of Coronary Heart Disease and Ischemic Stroke" @default.
- W2952316204 cites W1948122400 @default.
- W2952316204 cites W1973696556 @default.
- W2952316204 cites W1976428272 @default.
- W2952316204 cites W1978470249 @default.
- W2952316204 cites W1980482097 @default.
- W2952316204 cites W1999610776 @default.
- W2952316204 cites W2006497586 @default.
- W2952316204 cites W2006551863 @default.
- W2952316204 cites W2010457736 @default.
- W2952316204 cites W2010922475 @default.
- W2952316204 cites W2036747551 @default.
- W2952316204 cites W2040770080 @default.
- W2952316204 cites W2041380076 @default.
- W2952316204 cites W2050838276 @default.
- W2952316204 cites W2054869306 @default.
- W2952316204 cites W2067395123 @default.
- W2952316204 cites W2091126023 @default.
- W2952316204 cites W2097572487 @default.
- W2952316204 cites W2102450945 @default.
- W2952316204 cites W2105281057 @default.
- W2952316204 cites W2108790161 @default.
- W2952316204 cites W2112848098 @default.
- W2952316204 cites W2115801316 @default.
- W2952316204 cites W2117292999 @default.
- W2952316204 cites W2117419192 @default.
- W2952316204 cites W2121187319 @default.
- W2952316204 cites W2138595885 @default.
- W2952316204 cites W2144516660 @default.
- W2952316204 cites W2146224317 @default.
- W2952316204 cites W2148195524 @default.
- W2952316204 cites W2153118028 @default.
- W2952316204 cites W2159738130 @default.
- W2952316204 cites W2163969089 @default.
- W2952316204 cites W2166450210 @default.
- W2952316204 cites W2167717479 @default.
- W2952316204 cites W2169276865 @default.
- W2952316204 cites W2170009139 @default.
- W2952316204 cites W2216998043 @default.
- W2952316204 cites W2261389324 @default.
- W2952316204 cites W2294822677 @default.
- W2952316204 cites W2314618209 @default.
- W2952316204 cites W2323589075 @default.
- W2952316204 cites W2333888269 @default.
- W2952316204 cites W2407228972 @default.
- W2952316204 cites W2547258893 @default.
- W2952316204 cites W2564394847 @default.
- W2952316204 cites W2571030186 @default.
- W2952316204 cites W2748122449 @default.
- W2952316204 cites W2774002207 @default.
- W2952316204 cites W2798162979 @default.
- W2952316204 cites W2806174733 @default.
- W2952316204 cites W2885573893 @default.
- W2952316204 cites W3216513478 @default.
- W2952316204 cites W416868247 @default.
- W2952316204 cites W4293084779 @default.
- W2952316204 doi "https://doi.org/10.7150/ijms.31729" @default.
- W2952316204 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6643107" @default.
- W2952316204 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31337960" @default.
- W2952316204 hasPublicationYear "2019" @default.
- W2952316204 type Work @default.
- W2952316204 sameAs 2952316204 @default.
- W2952316204 citedByCount "6" @default.
- W2952316204 countsByYear W29523162042020 @default.
- W2952316204 countsByYear W29523162042021 @default.
- W2952316204 countsByYear W29523162042022 @default.
- W2952316204 crossrefType "journal-article" @default.
- W2952316204 hasAuthorship W2952316204A5014672450 @default.
- W2952316204 hasAuthorship W2952316204A5048457452 @default.
- W2952316204 hasAuthorship W2952316204A5068327668 @default.
- W2952316204 hasAuthorship W2952316204A5068795845 @default.
- W2952316204 hasAuthorship W2952316204A5069913517 @default.
- W2952316204 hasAuthorship W2952316204A5071951923 @default.
- W2952316204 hasBestOaLocation W29523162041 @default.
- W2952316204 hasConcept C104317684 @default.
- W2952316204 hasConcept C126322002 @default.
- W2952316204 hasConcept C134018914 @default.
- W2952316204 hasConcept C135763542 @default.
- W2952316204 hasConcept C139275648 @default.
- W2952316204 hasConcept C153209595 @default.
- W2952316204 hasConcept C180754005 @default.
- W2952316204 hasConcept C2908647359 @default.
- W2952316204 hasConcept C54355233 @default.
- W2952316204 hasConcept C71924100 @default.
- W2952316204 hasConcept C86803240 @default.
- W2952316204 hasConcept C90924648 @default.
- W2952316204 hasConcept C99454951 @default.
- W2952316204 hasConceptScore W2952316204C104317684 @default.