Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952325402> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2952325402 abstract "Derivatives of apomorphine and of N‐n‐propylnorapomorphine were prepared to obtain modified pharmacological activity and enhanced chemical stability. Mouse profile and dog emesis screens were performed, and the activity of various N‐substituted derivatives and their esters was evaluated and compared to the parent compounds. The N‐n‐propyl diacetate derivative and N‐methyl and N‐n‐propyl ascorbate salts were remarkably stable to air; apomorphine etherate was no more stable than the free base. The dimers, the major products formed during the acid‐catalyzed rearrangement of morphines to apomorphines, were all potent emetics. Additionally, two showed a significant antagonism to morphine in mice and dogs." @default.
- W2952325402 created "2019-06-27" @default.
- W2952325402 creator A5051014641 @default.
- W2952325402 creator A5052902014 @default.
- W2952325402 creator A5059605058 @default.
- W2952325402 creator A5074824881 @default.
- W2952325402 creator A5084533103 @default.
- W2952325402 creator A5065188427 @default.
- W2952325402 date "1977-04-05" @default.
- W2952325402 modified "2023-09-26" @default.
- W2952325402 title "ChemInform Abstract: DERIVATIVES OF APOMORPHINE AND OF OTHER N-SUBSTITUTED NORAPOMORPHINES" @default.
- W2952325402 cites W2055867230 @default.
- W2952325402 doi "https://doi.org/10.1002/chin.197714362" @default.
- W2952325402 hasPublicationYear "1977" @default.
- W2952325402 type Work @default.
- W2952325402 sameAs 2952325402 @default.
- W2952325402 citedByCount "0" @default.
- W2952325402 crossrefType "journal-article" @default.
- W2952325402 hasAuthorship W2952325402A5051014641 @default.
- W2952325402 hasAuthorship W2952325402A5052902014 @default.
- W2952325402 hasAuthorship W2952325402A5059605058 @default.
- W2952325402 hasAuthorship W2952325402A5065188427 @default.
- W2952325402 hasAuthorship W2952325402A5074824881 @default.
- W2952325402 hasAuthorship W2952325402A5084533103 @default.
- W2952325402 hasConcept C106159729 @default.
- W2952325402 hasConcept C111771559 @default.
- W2952325402 hasConcept C155647269 @default.
- W2952325402 hasConcept C162324750 @default.
- W2952325402 hasConcept C170493617 @default.
- W2952325402 hasConcept C185592680 @default.
- W2952325402 hasConcept C2777383412 @default.
- W2952325402 hasConcept C2777389121 @default.
- W2952325402 hasConcept C2777525119 @default.
- W2952325402 hasConcept C2778938600 @default.
- W2952325402 hasConcept C55493867 @default.
- W2952325402 hasConcept C71240020 @default.
- W2952325402 hasConcept C71924100 @default.
- W2952325402 hasConcept C98274493 @default.
- W2952325402 hasConceptScore W2952325402C106159729 @default.
- W2952325402 hasConceptScore W2952325402C111771559 @default.
- W2952325402 hasConceptScore W2952325402C155647269 @default.
- W2952325402 hasConceptScore W2952325402C162324750 @default.
- W2952325402 hasConceptScore W2952325402C170493617 @default.
- W2952325402 hasConceptScore W2952325402C185592680 @default.
- W2952325402 hasConceptScore W2952325402C2777383412 @default.
- W2952325402 hasConceptScore W2952325402C2777389121 @default.
- W2952325402 hasConceptScore W2952325402C2777525119 @default.
- W2952325402 hasConceptScore W2952325402C2778938600 @default.
- W2952325402 hasConceptScore W2952325402C55493867 @default.
- W2952325402 hasConceptScore W2952325402C71240020 @default.
- W2952325402 hasConceptScore W2952325402C71924100 @default.
- W2952325402 hasConceptScore W2952325402C98274493 @default.
- W2952325402 hasLocation W29523254021 @default.
- W2952325402 hasOpenAccess W2952325402 @default.
- W2952325402 hasPrimaryLocation W29523254021 @default.
- W2952325402 isParatext "false" @default.
- W2952325402 isRetracted "false" @default.
- W2952325402 magId "2952325402" @default.
- W2952325402 workType "article" @default.