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- W2952379493 abstract "Ultrasound, in concert with circulating microbubble contrast agents, has emerged as a promising modality for therapy and imaging of brain diseases. Despite progress, existing methods for correcting skull-related distortions require significant computation, which hampers their use in applications that require fast implementations, including adaptive focusing and tracking of the microbubble dynamics. While the angular spectrum approach (ASA)-a frequency domain method-can overcome these challenges, current implementations do not intrinsically account for heterogeneity in the propagation medium. Here, we derive the general solution for the ASA in a heterogeneous medium, we provide analytical solution for the special case of a stratified medium, and, subsequently, we evaluate these solutions for (human) skull-related aberration correction and trans-skull passive acoustic mapping. Collectively our findings indicate that the proposed phase correction method based on the ASA could provide a computationally efficient and accurate method for trans-skull focusing and imaging of point scatterers, potentially opening new possibilities for treatment and diagnosis of brain diseases." @default.
- W2952379493 created "2019-06-27" @default.
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- W2952379493 date "2019-06-19" @default.
- W2952379493 modified "2023-09-27" @default.
- W2952379493 title "Fast Acoustic Aberration Correction with the Angular Spectrum Approach" @default.
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