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- W2952380974 endingPage "4859" @default.
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- W2952380974 abstract "A highly efficient multicomponent reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, alcohol, and α,β-unsaturated aldehyde or ketone is disclosed, which generates the diverse H-pyrazolo[5,1-a]isoquinolines in good yields. This reaction proceeds with good functional group tolerance under mild conditions with high efficiency and excellent selectivity. Preliminary biological assays show that some of these compounds display promising activities as CDC25B inhibitor, TC-PTP inhibitor, and PTP1B inhibitor." @default.
- W2952380974 created "2019-06-27" @default.
- W2952380974 creator A5038839605 @default.
- W2952380974 creator A5074754590 @default.
- W2952380974 date "2010-09-27" @default.
- W2952380974 modified "2023-10-07" @default.
- W2952380974 title "Efficient Generation of Biologically Active <i>H</i>-Pyrazolo[5,1-<i>a</i>]isoquinolines via Multicomponent Reaction" @default.
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- W2952380974 doi "https://doi.org/10.1021/ol101988q" @default.
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