Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952391285> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2952391285 abstract "Forty years after the first reports on stimuli-responsive phase transitions in synthetic hydrogels, the first medicines based on responsive components are approaching the market. Sensitiveness to internal or external signals of the body can be achieved by means of materials (mostly polymers, but also lipids and metals) that modify their properties as a function of the intensity of the signal and that enable the transduction into changes in the delivery system that affect its ability to host/release a therapeutic substance. Integration of responsive materials into implantable depots, targetable nanocarriers and even insertable medical devices can endow them with activation-modulated and feedback-regulated control of drug release. This review offers a critical overview of therapeutically-interesting stimuli to trigger drug release and the evolution of responsive materials suitable as functional excipients, illustrated with recent examples of formulations in clinical trials or already commercially available, which can provide a perspective on the current state of the art on smart drug delivery systems." @default.
- W2952391285 created "2019-06-27" @default.
- W2952391285 creator A5079536963 @default.
- W2952391285 date "2014-08-14" @default.
- W2952391285 modified "2023-10-18" @default.
- W2952391285 title "ChemInform Abstract: Smart Drug Delivery Systems: From Fundamentals to the Clinic" @default.
- W2952391285 cites W2036641299 @default.
- W2952391285 doi "https://doi.org/10.1002/chin.201435273" @default.
- W2952391285 hasPublicationYear "2014" @default.
- W2952391285 type Work @default.
- W2952391285 sameAs 2952391285 @default.
- W2952391285 citedByCount "0" @default.
- W2952391285 crossrefType "journal-article" @default.
- W2952391285 hasAuthorship W2952391285A5079536963 @default.
- W2952391285 hasConcept C163588942 @default.
- W2952391285 hasConcept C171250308 @default.
- W2952391285 hasConcept C178790620 @default.
- W2952391285 hasConcept C18150654 @default.
- W2952391285 hasConcept C185592680 @default.
- W2952391285 hasConcept C192562407 @default.
- W2952391285 hasConcept C2779820397 @default.
- W2952391285 hasConcept C2780035454 @default.
- W2952391285 hasConcept C521977710 @default.
- W2952391285 hasConcept C62773188 @default.
- W2952391285 hasConcept C71924100 @default.
- W2952391285 hasConcept C98274493 @default.
- W2952391285 hasConceptScore W2952391285C163588942 @default.
- W2952391285 hasConceptScore W2952391285C171250308 @default.
- W2952391285 hasConceptScore W2952391285C178790620 @default.
- W2952391285 hasConceptScore W2952391285C18150654 @default.
- W2952391285 hasConceptScore W2952391285C185592680 @default.
- W2952391285 hasConceptScore W2952391285C192562407 @default.
- W2952391285 hasConceptScore W2952391285C2779820397 @default.
- W2952391285 hasConceptScore W2952391285C2780035454 @default.
- W2952391285 hasConceptScore W2952391285C521977710 @default.
- W2952391285 hasConceptScore W2952391285C62773188 @default.
- W2952391285 hasConceptScore W2952391285C71924100 @default.
- W2952391285 hasConceptScore W2952391285C98274493 @default.
- W2952391285 hasLocation W29523912851 @default.
- W2952391285 hasOpenAccess W2952391285 @default.
- W2952391285 hasPrimaryLocation W29523912851 @default.
- W2952391285 hasRelatedWork W2029623098 @default.
- W2952391285 hasRelatedWork W2036641299 @default.
- W2952391285 hasRelatedWork W2064278520 @default.
- W2952391285 hasRelatedWork W2080523820 @default.
- W2952391285 hasRelatedWork W2107660675 @default.
- W2952391285 hasRelatedWork W2118330521 @default.
- W2952391285 hasRelatedWork W2161807038 @default.
- W2952391285 hasRelatedWork W2334955167 @default.
- W2952391285 hasRelatedWork W2473783270 @default.
- W2952391285 hasRelatedWork W2598610410 @default.
- W2952391285 hasRelatedWork W2804601007 @default.
- W2952391285 hasRelatedWork W2809151977 @default.
- W2952391285 hasRelatedWork W2910979548 @default.
- W2952391285 hasRelatedWork W3048931336 @default.
- W2952391285 hasRelatedWork W3098394587 @default.
- W2952391285 hasRelatedWork W3152810395 @default.
- W2952391285 hasRelatedWork W3163804934 @default.
- W2952391285 hasRelatedWork W3194329811 @default.
- W2952391285 hasRelatedWork W3203381395 @default.
- W2952391285 hasRelatedWork W3087716736 @default.
- W2952391285 isParatext "false" @default.
- W2952391285 isRetracted "false" @default.
- W2952391285 magId "2952391285" @default.
- W2952391285 workType "article" @default.