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- W2952416831 abstract "This chapter outlines the history of peptide chemistry that stretches over a hundred years, from compounds as simple as diglycine to enzymes with more than a hundred amino acids. On the basis of the individual character of each amino acid and enhanced by the combination of many amino acids to form larger molecules, peptides exert a wide variety of specific functions. They act as chemical messengers, hormones in the strict sense, intra or intercellular mediators, highly specific stimulators and inhibitors, and as biologically active peptides in the brain and nervous system. Peptides actively involved in reactions of the immune system are attracting increasing attention from biomedical researchers. Peptide science is still in full development. Several years ago, peptide chemists were concerned that the recombinant protein technology would replace the art of classic manufacturing. Looking back over the 1980s and 1990s, it now appears that a large number of valuable polypeptides are produced by genetic methods but the innumerable syntheses of medium sized peptides are still being performed in the chemical laboratory. In addition, the need for incorporation of unconventional building blocks into interesting products requires the skill and techniques involved in chemical peptide synthesis." @default.
- W2952416831 created "2019-06-27" @default.
- W2952416831 creator A5065143545 @default.
- W2952416831 date "1995-01-01" @default.
- W2952416831 modified "2023-09-26" @default.
- W2952416831 title "The History of Peptide Chemistry" @default.
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