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• W2952482783 abstract "The formal synthesis of D,L-hapalindole O has been accomplished intercepting Natsume's total synthesis route. The intercepted substrate was synthesized in an overall 36% yield over ten-synthetic steps compared to Natsume's overall 1% yield over eighteen-synthetic steps. In addition, advanced substrates for the continuing progress towards hapalindole K and ambiguine A has been synthesized. All routes described herein employ a novel silyl ether-based strategy accessing the 6:5:6:6 ring system, that has previously been used in our laboratory to access the total synthesis of D,L-hapalindoles J and U." @default.
• W2952482783 created "2019-06-27" @default.
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• W2952482783 date "2012-01-01" @default.
• W2952482783 modified "2023-10-14" @default.
• W2952482783 title "Formal Synthesis of Hapalindole O and Synthetic Efforts towards Hapalindole K and Ambiguine A" @default.
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• W2952482783 doi "https://doi.org/10.3987/com-12-s(n)3" @default.
• W2952482783 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4010148" @default.
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