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- W2952595483 abstract "A plenty of human efforts is necessary to perform simply repeating processes such as preparations of synthetic intermediates and building blocks, optimizations of reaction conditions and couplings of building blocks in syntheses of natural products and their analogue libraries. These efforts can be reduced by using an automated synthesis apparatus. It is expected that laboratory automation can realize highly efficient, reproducible and safe synthesis of organic compounds. We report here the application of single reactor automated synthesizers to supply of a synthetic key intermediate of taxol and to preparation of monosaccharide building blocks toward combinatorial oligosaccharide library synthesis. In addition, we also applied multi reactor automated synthesizers to optimization of a primary amide N-glycosylation and to one-pot parallel syntheses of phytoalexin elicitor active oligosaccharides library and LewisX/dimeric LewisX library." @default.
- W2952595483 created "2019-06-27" @default.
- W2952595483 creator A5043899233 @default.
- W2952595483 date "2011-01-01" @default.
- W2952595483 modified "2023-09-25" @default.
- W2952595483 title "Efficient Syntheses of Natural Products and Their Analogues Using Laboratory Automation Technology" @default.
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- W2952595483 doi "https://doi.org/10.5059/yukigoseikyokaishi.69.379" @default.
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