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• W2952641491 abstract "A series of modifications were made to the C-3 substituent of the 1,5-benzodiazepine CCK-A agonist 1. Replacement of the inner urea NH and addition of a methyl group to generate a C-3 quaternary carbon resulted in acetamide 6, which showed CCK-A receptor binding selectivity and sub-micromolar agonist activity in vitro. Benzodiazepine 6 was active in an in vivo mouse gallbladder emptying assay and represents a novel orally active, binding selective CCK-A agonist." @default.
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• W2952641491 date "1996-01-01" @default.
• W2952641491 modified "2023-09-23" @default.
• W2952641491 title "3-[2-(<i>N</i>-Phenylacetamide)]-1,5-benzodiazepines: Orally Active, Binding Selective CCK-A Agonists" @default.
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• W2952641491 doi "https://doi.org/10.1021/jm960205b" @default.
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