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- W2952717745 abstract "The synthesis of a series of new 4-[(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)alkoxycarbonyl]-1-(diphenylmethyl)piperazines 2 by phase-transfer catalysed monoalkoxycarbonylation of α,ω-dichloroalkanes is described. Compounds 2 are related to oxatomide1) (1) and are potential histamine-H1 antagonists. A study on the regioselective preparation of substituted 1,3-dihydro-1-isopropenyl-2H-benzimidazol-2-ones (5) was also carried out.Potentielle H1-Antihistaminica: Synthese von 4-[(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)alkoxycarbonyl]-1-(diphenylmethyl)piperazinen durch selektive Phasen-Transfer-katalysierte Monoalkoxycarbonylierung von α,ω-DichloralkanenDie Synthese einer Reihe von neuen 4-[(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)alkoxycarbonyl]-1-(diphenylmethyl)piperazinen 2 durch Phasen-Transfer-katalysierte Monoalkoxycarbonylierung von α,ω-Dichloralkanen wird beschrieben. Die Piperazine 2 ahneln Oxatomid1) (1) und sind potentielle H1-Antihistaminica. Ferner wurde eine Untersuchung zur regioselektiven Synthese von substituierten 1,3-Dihydro-1-isopropenyl-2H-benzimidazol-2-onen (5) durchgefuhrt." @default.
- W2952717745 created "2019-06-27" @default.
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- W2952717745 creator A5051331036 @default.
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- W2952717745 date "1989-09-19" @default.
- W2952717745 modified "2023-10-05" @default.
- W2952717745 title "ChemInform Abstract: Potential H1-Antihistaminic Drugs: Synthesis of 4-((2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)alkoxycarbonyl)-1-(diphenylmethyl)piperazines by Selective Monoalkoxycarbonylation of α,ω-Dichloroalkanes by Phase-Transfer Catalysis." @default.
- W2952717745 cites W2018863981 @default.
- W2952717745 doi "https://doi.org/10.1002/chin.198938253" @default.
- W2952717745 hasPublicationYear "1989" @default.
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