Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952772728> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2952772728 endingPage "e153" @default.
- W2952772728 startingPage "e153" @default.
- W2952772728 abstract "Objective: Proinflammatory status is the risk factor for coronary atherosclerosis progression after coronary stenting (CS). Intensive statin treatment is associated with high-sensitivity C-reactive protein (hsCRP) concentration decline. We aimed to evaluate prognostic significance of preprocedural hsCRP level reduction with intensive statin regimen for coronary atherosclerosis progression during one year after CS. Design and method: We enrolled 102 patients with stable angina who were on list for scheduled CS. Group I (n = 37) patients received atorvastatin 80 mg for 7 days before and 3 months after CS with further dose adjustment according to LDL; group II (n = 65) patients received atorvastatin 20–40 mg/day for LDL goal achievement. HsCRP level was assessed at baseline, before CS and after 1, 3, 6 and 12 months. Coronary atherosclerosis progression was defined as new >50% stenosis or >30% increase of >20% pre-existing stenosis according to coronary angiography (CA) 1 year after CS. Results: Baseline concentration of hsCRP was comparable: 0.21 (0.13;0.38) vs. 0.20 (0.1;0.44) mg/dl in groups I and II, respectively (p>0.05). In group I significant hsCRP level decrease to 0,14 (0.07;0.32) mg/dl, p < 0.05) was determined after 7 days. Coronary atherosclerosis progression was revealed in 10 (41%) patients in group I and in 20 (47%) in group II according to CA. HsCRP level >0.26 was associated with coronary atherosclerosis progression during 12 months (OR 4.2 for total study group, 95% CI 1.4–12.3; p = 0.01). Conclusions: Elevated preprocedural hsCRP level is associated with coronary atherosclerosis progression after CS. Intensive atorvastatin regimen for one week before CS leads to preprocedural hsCRP level reduction." @default.
- W2952772728 created "2019-06-27" @default.
- W2952772728 creator A5015696467 @default.
- W2952772728 creator A5016758570 @default.
- W2952772728 creator A5023692470 @default.
- W2952772728 creator A5025704138 @default.
- W2952772728 creator A5027780622 @default.
- W2952772728 creator A5032313132 @default.
- W2952772728 creator A5066567869 @default.
- W2952772728 creator A5073545005 @default.
- W2952772728 creator A5076960623 @default.
- W2952772728 creator A5079002531 @default.
- W2952772728 creator A5080946603 @default.
- W2952772728 creator A5082801788 @default.
- W2952772728 date "2019-07-01" @default.
- W2952772728 modified "2023-10-06" @default.
- W2952772728 title "PREPROCEDURAL HIGH-SENSITIVITY C-REACTIVE PROTEIN DECREASE DURING INTENSIVE ATORVASTATIN THERAPY" @default.
- W2952772728 doi "https://doi.org/10.1097/01.hjh.0000571960.98238.94" @default.
- W2952772728 hasPublicationYear "2019" @default.
- W2952772728 type Work @default.
- W2952772728 sameAs 2952772728 @default.
- W2952772728 citedByCount "0" @default.
- W2952772728 crossrefType "journal-article" @default.
- W2952772728 hasAuthorship W2952772728A5015696467 @default.
- W2952772728 hasAuthorship W2952772728A5016758570 @default.
- W2952772728 hasAuthorship W2952772728A5023692470 @default.
- W2952772728 hasAuthorship W2952772728A5025704138 @default.
- W2952772728 hasAuthorship W2952772728A5027780622 @default.
- W2952772728 hasAuthorship W2952772728A5032313132 @default.
- W2952772728 hasAuthorship W2952772728A5066567869 @default.
- W2952772728 hasAuthorship W2952772728A5073545005 @default.
- W2952772728 hasAuthorship W2952772728A5076960623 @default.
- W2952772728 hasAuthorship W2952772728A5079002531 @default.
- W2952772728 hasAuthorship W2952772728A5080946603 @default.
- W2952772728 hasAuthorship W2952772728A5082801788 @default.
- W2952772728 hasConcept C126322002 @default.
- W2952772728 hasConcept C164705383 @default.
- W2952772728 hasConcept C2776839432 @default.
- W2952772728 hasConcept C2776914184 @default.
- W2952772728 hasConcept C2777482532 @default.
- W2952772728 hasConcept C2777698277 @default.
- W2952772728 hasConcept C2778213512 @default.
- W2952772728 hasConcept C2781195455 @default.
- W2952772728 hasConcept C2781413609 @default.
- W2952772728 hasConcept C2991716557 @default.
- W2952772728 hasConcept C500558357 @default.
- W2952772728 hasConcept C71924100 @default.
- W2952772728 hasConcept C90924648 @default.
- W2952772728 hasConceptScore W2952772728C126322002 @default.
- W2952772728 hasConceptScore W2952772728C164705383 @default.
- W2952772728 hasConceptScore W2952772728C2776839432 @default.
- W2952772728 hasConceptScore W2952772728C2776914184 @default.
- W2952772728 hasConceptScore W2952772728C2777482532 @default.
- W2952772728 hasConceptScore W2952772728C2777698277 @default.
- W2952772728 hasConceptScore W2952772728C2778213512 @default.
- W2952772728 hasConceptScore W2952772728C2781195455 @default.
- W2952772728 hasConceptScore W2952772728C2781413609 @default.
- W2952772728 hasConceptScore W2952772728C2991716557 @default.
- W2952772728 hasConceptScore W2952772728C500558357 @default.
- W2952772728 hasConceptScore W2952772728C71924100 @default.
- W2952772728 hasConceptScore W2952772728C90924648 @default.
- W2952772728 hasLocation W29527727281 @default.
- W2952772728 hasOpenAccess W2952772728 @default.
- W2952772728 hasPrimaryLocation W29527727281 @default.
- W2952772728 hasRelatedWork W2011059280 @default.
- W2952772728 hasRelatedWork W2041975298 @default.
- W2952772728 hasRelatedWork W2087688421 @default.
- W2952772728 hasRelatedWork W2354698137 @default.
- W2952772728 hasRelatedWork W2354846095 @default.
- W2952772728 hasRelatedWork W2371402485 @default.
- W2952772728 hasRelatedWork W2387430426 @default.
- W2952772728 hasRelatedWork W2794101207 @default.
- W2952772728 hasRelatedWork W2950712637 @default.
- W2952772728 hasRelatedWork W3027017808 @default.
- W2952772728 hasVolume "37" @default.
- W2952772728 isParatext "false" @default.
- W2952772728 isRetracted "false" @default.
- W2952772728 magId "2952772728" @default.
- W2952772728 workType "article" @default.