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- W2952806583 abstract "Antiviral activity of 1,3-disubstituted uracil derivatives was evaluated against HIV-1 and HCMV. It appears that the nitrogen of the 1-cyanomethyl group is important for anti-HIV-1 activity, suggesting interaction with the amino acid residues of HIV-1 reverse transcriptase. 1-Arylmethyl derivatives also exhibited good anti-HIV-1 activity; and that of the 2- and 4-picolyl derivatives was particularly excellent." @default.
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- W2952806583 date "2008-03-25" @default.
- W2952806583 modified "2023-09-24" @default.
- W2952806583 title "ChemInform Abstract: Antiviral Activity of 3-(3,5-Dimethylbenzyl)uracil Derivatives Against HIV-1 and HCMV" @default.
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- W2952806583 doi "https://doi.org/10.1002/chin.200813255" @default.
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