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- W2952817401 abstract "As part of a search for new synthetic antibacterial agents to combat systemic infection, various analogues of 7-oxo-2, 3-dihydro-7H-pyrido [1, 2, 3-de] [1, 4] benzoxazine-6-carboxylic acids were synthesized. Among the compounds newly synthesized, 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2, 3-dihydro-7H-pyrido [1, 2, 3-de] [1, 4] benzoxazine-6-carboxylic acid (DL-8280) showed potent antibacterial activity against Gram-positive and-negative pathogens, including Psedomonas aeruginosa, and its metabolic disposition was shown in separate experimentals to be favorable." @default.
- W2952817401 created "2019-06-27" @default.
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- W2952817401 creator A5019871387 @default.
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- W2952817401 date "1985-06-04" @default.
- W2952817401 modified "2023-09-24" @default.
- W2952817401 title "ChemInform Abstract: SYNTHESIS AND ANTIBACTERIAL ACTIVITIES OF SUBSTITUTED 7-OXO-2,3-DIHYDRO-7H-PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACIDS" @default.
- W2952817401 cites W2322477540 @default.
- W2952817401 doi "https://doi.org/10.1002/chin.198522250" @default.
- W2952817401 hasPublicationYear "1985" @default.
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