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- W2952884723 abstract "Abstract As scleractinian coral cover declines in the face of increased frequency in disease outbreaks, future reefs may become dominated by octocorals. Understanding octocoral disease responses and consequences is therefore necessary if we are to gain insight into the future of ecosystem services provided by coral reefs. In Florida, populations of the octocoral Eunicea calyculata infected with Eunicea black disease (EBD) were observed in the field in the fall of 2011. This disease was recognized by a stark, black pigmentation caused by heavy melanization. Histological preparations of E. calyculata infected with EBD demonstrated granular amoebocyte (GA) mobilization, melanin granules in much of the GA population, and the presence of fungal hyphae penetrating coral tissue. Previous transcriptomic analysis also identified immune trade-offs evidenced by increased immune investment at the expense of growth. Our investigation utilized proteogenomic techniques to reveal decreased investment in general cell signaling while increasing energy production for immune responses. Inflammation was also prominent in diseased E. calyculata and sheds light on factors driving the extreme phenotype observed with EBD. With disease outbreaks continuing to increase in frequency, our results highlight new targets within the cnidarian immune system and provide a framework for understanding transcriptomics in the context of an organismal disease phenotype and its protein expression." @default.
- W2952884723 created "2019-06-27" @default.
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- W2952884723 date "2019-06-21" @default.
- W2952884723 modified "2023-09-25" @default.
- W2952884723 title "Proteomic Investigation of a Diseased Gorgonian Coral Indicates Disruption of Essential Cell Function and Investment in Inflammatory and Other Immune Processes" @default.
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- W2952884723 cites W1766122222 @default.
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- W2952884723 cites W1863743272 @default.
- W2952884723 cites W1947236484 @default.
- W2952884723 cites W1965688385 @default.
- W2952884723 cites W1966954153 @default.
- W2952884723 cites W1979971768 @default.
- W2952884723 cites W1999810095 @default.
- W2952884723 cites W2005682388 @default.
- W2952884723 cites W2008883486 @default.
- W2952884723 cites W2009858080 @default.
- W2952884723 cites W2016071629 @default.
- W2952884723 cites W2018544314 @default.
- W2952884723 cites W2026433130 @default.
- W2952884723 cites W2027933379 @default.
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- W2952884723 cites W2075752200 @default.
- W2952884723 cites W2077594489 @default.
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- W2952884723 cites W2079279399 @default.
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- W2952884723 cites W2101911260 @default.
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- W2952884723 cites W2112962121 @default.
- W2952884723 cites W2113040994 @default.
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- W2952884723 cites W2123693233 @default.
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- W2952884723 cites W2280001637 @default.
- W2952884723 cites W2293040502 @default.
- W2952884723 cites W2337839574 @default.
- W2952884723 cites W2339356454 @default.
- W2952884723 cites W2408017125 @default.
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- W2952884723 cites W2516341338 @default.
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- W2952884723 doi "https://doi.org/10.1093/icb/icz107" @default.
- W2952884723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31225585" @default.
- W2952884723 hasPublicationYear "2019" @default.
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