FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952918093> ?p ?o ?g. }

• W2952918093 endingPage "1672" @default.
• W2952918093 startingPage "1663" @default.
• W2952918093 abstract "Dosage compensation has evolved in concert with Y-chromosome degeneration in many taxa that exhibit heterogametic sex chromosomes. Dosage compensation overcomes the biological challenge of a half dose of X chromosome gene transcripts in the heterogametic sex. The need to equalize gene expression of a hemizygous X with that of autosomes arises from the fact that the X chromosomes retain hundreds of functional genes that are actively transcribed in both sexes and interact with genes expressed on the autosomes. Sex determination and heterogametic sex chromosomes have evolved multiple times in Diptera, and in each case the genetic control of dosage compensation is tightly linked to sex determination. In the Anopheles gambiae species complex (Culicidae), maleness is conferred by the Y-chromosome gene Yob, which despite its conserved role between species is polymorphic in its copy number between them. Previous work demonstrated that male An. gambiae s.s. males exhibit complete dosage compensation in pupal and adult stages. In the present study, we have extended this analysis to three sister species in the An. gambiae complex: An. coluzzii, An. arabiensis, and An. quadriannulatus. In addition, we analyzed dosage compensation in bi-directional F1 hybrids between these species to determine if hybridization results in the mis-regulation and disruption of dosage compensation. Our results confirm that dosage compensation operates in the An. gambiae species complex through the hypertranscription of the male X chromosome. Additionally, dosage compensation in hybrid males does not differ from parental males, indicating that hybridization does not result in the mis-regulation of dosage compensation." @default.
• W2952918093 created "2019-06-27" @default.
• W2952918093 creator A5063353745 @default.
• W2952918093 creator A5072396187 @default.
• W2952918093 creator A5078029996 @default.
• W2952918093 date "2018-06-01" @default.
• W2952918093 modified "2023-09-26" @default.
• W2952918093 title "The Effect of Hybridization on Dosage Compensation in Member Species of the Anopheles gambiae Species Complex" @default.
• W2952918093 cites W1577605596 @default.
• W2952918093 cites W1878468064 @default.
• W2952918093 cites W1889629465 @default.
• W2952918093 cites W1955378566 @default.
• W2952918093 cites W1967470558 @default.
• W2952918093 cites W1988325516 @default.
• W2952918093 cites W1991669878 @default.
• W2952918093 cites W1992885695 @default.
• W2952918093 cites W1996332055 @default.
• W2952918093 cites W2006249897 @default.
• W2952918093 cites W2014538668 @default.
• W2952918093 cites W2023994991 @default.
• W2952918093 cites W2029098371 @default.
• W2952918093 cites W2041282815 @default.
• W2952918093 cites W2041358828 @default.
• W2952918093 cites W2053551770 @default.
• W2952918093 cites W2057307047 @default.
• W2952918093 cites W2070076204 @default.
• W2952918093 cites W2076635391 @default.
• W2952918093 cites W2084518266 @default.
• W2952918093 cites W2088194699 @default.
• W2952918093 cites W2100448568 @default.
• W2952918093 cites W2108234281 @default.
• W2952918093 cites W2117936709 @default.
• W2952918093 cites W2121878323 @default.
• W2952918093 cites W2122152054 @default.
• W2952918093 cites W2124354102 @default.
• W2952918093 cites W2127991390 @default.
• W2952918093 cites W2129424985 @default.
• W2952918093 cites W2131271579 @default.
• W2952918093 cites W2131400772 @default.
• W2952918093 cites W2135112382 @default.
• W2952918093 cites W2136104403 @default.
• W2952918093 cites W2136417358 @default.
• W2952918093 cites W2139067647 @default.
• W2952918093 cites W2146902920 @default.
• W2952918093 cites W2155150900 @default.
• W2952918093 cites W2155896486 @default.
• W2952918093 cites W2157227311 @default.
• W2952918093 cites W2159816002 @default.
• W2952918093 cites W2169456326 @default.
• W2952918093 cites W2170551349 @default.
• W2952918093 cites W2172146312 @default.
• W2952918093 cites W2203004090 @default.
• W2952918093 cites W2235028661 @default.
• W2952918093 cites W2280681614 @default.
• W2952918093 cites W2313423684 @default.
• W2952918093 cites W2318802957 @default.
• W2952918093 cites W2467960033 @default.
• W2952918093 cites W2498243082 @default.
• W2952918093 cites W2760192776 @default.
• W2952918093 cites W2951047006 @default.
• W2952918093 cites W3105872783 @default.
• W2952918093 cites W4298872162 @default.
• W2952918093 doi "https://doi.org/10.1093/gbe/evy108" @default.
• W2952918093 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6037052" @default.
• W2952918093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29860336" @default.
• W2952918093 hasPublicationYear "2018" @default.
• W2952918093 type Work @default.
• W2952918093 sameAs 2952918093 @default.
• W2952918093 citedByCount "6" @default.
• W2952918093 countsByYear W29529180932018 @default.
• W2952918093 countsByYear W29529180932019 @default.
• W2952918093 countsByYear W29529180932020 @default.
• W2952918093 countsByYear W29529180932021 @default.
• W2952918093 crossrefType "journal-article" @default.
• W2952918093 hasAuthorship W2952918093A5063353745 @default.
• W2952918093 hasAuthorship W2952918093A5072396187 @default.
• W2952918093 hasAuthorship W2952918093A5078029996 @default.
• W2952918093 hasBestOaLocation W29529180931 @default.
• W2952918093 hasConcept C104317684 @default.
• W2952918093 hasConcept C134925867 @default.
• W2952918093 hasConcept C148196450 @default.
• W2952918093 hasConcept C150194340 @default.
• W2952918093 hasConcept C203014093 @default.
• W2952918093 hasConcept C2776802408 @default.
• W2952918093 hasConcept C2778048844 @default.
• W2952918093 hasConcept C30481170 @default.
• W2952918093 hasConcept C35158069 @default.
• W2952918093 hasConcept C36217612 @default.
• W2952918093 hasConcept C48189365 @default.
• W2952918093 hasConcept C54355233 @default.
• W2952918093 hasConcept C55548728 @default.
• W2952918093 hasConcept C59822182 @default.
• W2952918093 hasConcept C78458016 @default.
• W2952918093 hasConcept C86803240 @default.
• W2952918093 hasConcept C92509807 @default.
• W2952918093 hasConceptScore W2952918093C104317684 @default.
• W2952918093 hasConceptScore W2952918093C134925867 @default.
• W2952918093 hasConceptScore W2952918093C148196450 @default.

• next