FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952919948> ?p ?o ?g. }

• W2952919948 abstract "Infections in the post-acute phase of cerebral ischaemia impede optimal recovery by exacerbating morbidity and mortality. Our review aims to reconcile the increased infection susceptibility of patients post-stroke by consolidating our understanding of compartmentalised alterations to systemic immunity. Mounting evidence has catalogued alterations to numerous immune cell populations but an understanding of the mechanisms of long-range communication between the immune system, nervous system and other organs beyond the involvement of autonomic signalling is lacking. By taking our cues from established and emerging concepts of neuro-immune interactions, immune-mediated inter-organ cross-talk, innate immune training and the role of microbiota-derived signals in central nervous system (CNS) function we will explore mechanisms of how cerebral ischaemia could shape systemic immune function. In this context, we will also discuss a key question: how are immune requirements critical for mediating repair of the ischaemic insult balanced by the need for anti-microbial immunity post-stroke, given that they are mediated by mutually exclusive immune networks? Our reformed understanding of the immune landscape post-stroke and novel mechanisms at play could guide targeted therapeutic interventions and initiate a step-change in the clinical management of these infectious complications post-stroke." @default.
• W2952919948 created "2019-06-27" @default.
• W2952919948 creator A5071765895 @default.
• W2952919948 creator A5081989291 @default.
• W2952919948 date "2019-07-02" @default.
• W2952919948 modified "2023-09-27" @default.
• W2952919948 title "Old Dog New Tricks; Revisiting How Stroke Modulates the Systemic Immune Landscape" @default.
• W2952919948 cites W1191698374 @default.
• W2952919948 cites W1483521748 @default.
• W2952919948 cites W1494319831 @default.
• W2952919948 cites W1519171461 @default.
• W2952919948 cites W1588685142 @default.
• W2952919948 cites W1653299435 @default.
• W2952919948 cites W1837173688 @default.
• W2952919948 cites W1869691464 @default.
• W2952919948 cites W1887418304 @default.
• W2952919948 cites W1918968064 @default.
• W2952919948 cites W1943222423 @default.
• W2952919948 cites W1966277943 @default.
• W2952919948 cites W1967763328 @default.
• W2952919948 cites W1974253654 @default.
• W2952919948 cites W1977211310 @default.
• W2952919948 cites W1977761329 @default.
• W2952919948 cites W1979590738 @default.
• W2952919948 cites W1981724301 @default.
• W2952919948 cites W1985585453 @default.
• W2952919948 cites W1988100193 @default.
• W2952919948 cites W1988902564 @default.
• W2952919948 cites W1995959583 @default.
• W2952919948 cites W1996024251 @default.
• W2952919948 cites W1996064706 @default.
• W2952919948 cites W1997414660 @default.
• W2952919948 cites W1999235115 @default.
• W2952919948 cites W1999615949 @default.
• W2952919948 cites W1999696784 @default.
• W2952919948 cites W2003666061 @default.
• W2952919948 cites W2004002514 @default.
• W2952919948 cites W2008188979 @default.
• W2952919948 cites W2012610329 @default.
• W2952919948 cites W2017850724 @default.
• W2952919948 cites W2018996778 @default.
• W2952919948 cites W2020983205 @default.
• W2952919948 cites W2021235791 @default.
• W2952919948 cites W2023749167 @default.
• W2952919948 cites W2024494773 @default.
• W2952919948 cites W2025369883 @default.
• W2952919948 cites W2026208410 @default.
• W2952919948 cites W2030047402 @default.
• W2952919948 cites W2030991207 @default.
• W2952919948 cites W2039176792 @default.
• W2952919948 cites W2043067098 @default.
• W2952919948 cites W2045012389 @default.
• W2952919948 cites W2045806619 @default.
• W2952919948 cites W2048469790 @default.
• W2952919948 cites W2048599333 @default.
• W2952919948 cites W2054808059 @default.
• W2952919948 cites W2056793603 @default.
• W2952919948 cites W2058602100 @default.
• W2952919948 cites W2058669152 @default.
• W2952919948 cites W2060130170 @default.
• W2952919948 cites W2063928404 @default.
• W2952919948 cites W2067401763 @default.
• W2952919948 cites W2067458787 @default.
• W2952919948 cites W2068238533 @default.
• W2952919948 cites W2068714945 @default.
• W2952919948 cites W2069368135 @default.
• W2952919948 cites W2069943416 @default.
• W2952919948 cites W2074974933 @default.
• W2952919948 cites W2077553363 @default.
• W2952919948 cites W2077720998 @default.
• W2952919948 cites W2080898127 @default.
• W2952919948 cites W2084147470 @default.
• W2952919948 cites W2085281517 @default.
• W2952919948 cites W2085695854 @default.
• W2952919948 cites W2086243699 @default.
• W2952919948 cites W2088299611 @default.
• W2952919948 cites W2091399990 @default.
• W2952919948 cites W2094558708 @default.
• W2952919948 cites W2095214727 @default.
• W2952919948 cites W2106329493 @default.
• W2952919948 cites W2112858189 @default.
• W2952919948 cites W2114303594 @default.
• W2952919948 cites W2117007782 @default.
• W2952919948 cites W2118200665 @default.
• W2952919948 cites W2118482193 @default.
• W2952919948 cites W2119042925 @default.
• W2952919948 cites W2119610102 @default.
• W2952919948 cites W2120321064 @default.
• W2952919948 cites W2125962445 @default.
• W2952919948 cites W2126625630 @default.
• W2952919948 cites W2127401626 @default.
• W2952919948 cites W2128337342 @default.
• W2952919948 cites W2128591402 @default.
• W2952919948 cites W2129613163 @default.
• W2952919948 cites W2132787792 @default.
• W2952919948 cites W2133956375 @default.
• W2952919948 cites W2137798077 @default.
• W2952919948 cites W2138526398 @default.
• W2952919948 cites W2141616905 @default.
• W2952919948 cites W2142132203 @default.

• next