Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952925259> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2952925259 endingPage "54" @default.
- W2952925259 startingPage "51" @default.
- W2952925259 abstract "The detection of PML/RARA or variant RARA rearrangements is critical for the diagnosis and treatment of patients with newly diagnosed acute promyelocytic leukemia (APL). While most cases of APL harboring the PML/RARA fusion respond to all-trans retinoic acid (ATRA), some variant RARA rearrangements are ATRA insensitive. Herein, we report a 27-year-old male with newly diagnosed, rapidly progressive APL and a rarely described STAT5B/RARA fusion with known resistance to ATRA therapy. While the PML/RARA dual-color dual-fusion fluorescence in situ hybridization (FISH) probe study was negative, the RARA break-apart probe study revealed an atypical RARA rearrangement in 95% of nuclei. A next generation sequencing assay, mate-pair sequencing, was subsequently performed to further characterize the RARA rearrangement and identified the RARA gene fusion partner STAT5B." @default.
- W2952925259 created "2019-06-27" @default.
- W2952925259 creator A5003913262 @default.
- W2952925259 creator A5015771837 @default.
- W2952925259 creator A5021419381 @default.
- W2952925259 creator A5030060042 @default.
- W2952925259 creator A5035077043 @default.
- W2952925259 creator A5053421382 @default.
- W2952925259 creator A5057465226 @default.
- W2952925259 creator A5057852407 @default.
- W2952925259 creator A5077968996 @default.
- W2952925259 creator A5079007941 @default.
- W2952925259 date "2019-09-01" @default.
- W2952925259 modified "2023-10-14" @default.
- W2952925259 title "Characterization of a rarely reported STAT5B/RARA gene fusion in a young adult with newly diagnosed acute promyelocytic leukemia with resistance to ATRA therapy" @default.
- W2952925259 cites W1553544241 @default.
- W2952925259 cites W1976165544 @default.
- W2952925259 cites W1981347116 @default.
- W2952925259 cites W2077872976 @default.
- W2952925259 cites W2135898904 @default.
- W2952925259 cites W2167810957 @default.
- W2952925259 cites W2174247300 @default.
- W2952925259 cites W2289598688 @default.
- W2952925259 cites W2584454437 @default.
- W2952925259 cites W2742021016 @default.
- W2952925259 cites W2759449463 @default.
- W2952925259 cites W2772104082 @default.
- W2952925259 cites W2895425110 @default.
- W2952925259 cites W2910602803 @default.
- W2952925259 doi "https://doi.org/10.1016/j.cancergen.2019.06.007" @default.
- W2952925259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31447065" @default.
- W2952925259 hasPublicationYear "2019" @default.
- W2952925259 type Work @default.
- W2952925259 sameAs 2952925259 @default.
- W2952925259 citedByCount "6" @default.
- W2952925259 countsByYear W29529252592020 @default.
- W2952925259 countsByYear W29529252592021 @default.
- W2952925259 countsByYear W29529252592022 @default.
- W2952925259 countsByYear W29529252592023 @default.
- W2952925259 crossrefType "journal-article" @default.
- W2952925259 hasAuthorship W2952925259A5003913262 @default.
- W2952925259 hasAuthorship W2952925259A5015771837 @default.
- W2952925259 hasAuthorship W2952925259A5021419381 @default.
- W2952925259 hasAuthorship W2952925259A5030060042 @default.
- W2952925259 hasAuthorship W2952925259A5035077043 @default.
- W2952925259 hasAuthorship W2952925259A5053421382 @default.
- W2952925259 hasAuthorship W2952925259A5057465226 @default.
- W2952925259 hasAuthorship W2952925259A5057852407 @default.
- W2952925259 hasAuthorship W2952925259A5077968996 @default.
- W2952925259 hasAuthorship W2952925259A5079007941 @default.
- W2952925259 hasConcept C104317684 @default.
- W2952925259 hasConcept C111829193 @default.
- W2952925259 hasConcept C2776601000 @default.
- W2952925259 hasConcept C2777542201 @default.
- W2952925259 hasConcept C2778461978 @default.
- W2952925259 hasConcept C2781121885 @default.
- W2952925259 hasConcept C30481170 @default.
- W2952925259 hasConcept C502942594 @default.
- W2952925259 hasConcept C54355233 @default.
- W2952925259 hasConcept C86803240 @default.
- W2952925259 hasConceptScore W2952925259C104317684 @default.
- W2952925259 hasConceptScore W2952925259C111829193 @default.
- W2952925259 hasConceptScore W2952925259C2776601000 @default.
- W2952925259 hasConceptScore W2952925259C2777542201 @default.
- W2952925259 hasConceptScore W2952925259C2778461978 @default.
- W2952925259 hasConceptScore W2952925259C2781121885 @default.
- W2952925259 hasConceptScore W2952925259C30481170 @default.
- W2952925259 hasConceptScore W2952925259C502942594 @default.
- W2952925259 hasConceptScore W2952925259C54355233 @default.
- W2952925259 hasConceptScore W2952925259C86803240 @default.
- W2952925259 hasLocation W29529252591 @default.
- W2952925259 hasLocation W29529252592 @default.
- W2952925259 hasOpenAccess W2952925259 @default.
- W2952925259 hasPrimaryLocation W29529252591 @default.
- W2952925259 hasRelatedWork W2038157705 @default.
- W2952925259 hasRelatedWork W2322323638 @default.
- W2952925259 hasRelatedWork W2347970638 @default.
- W2952925259 hasRelatedWork W2375265490 @default.
- W2952925259 hasRelatedWork W2382827349 @default.
- W2952925259 hasRelatedWork W2473873077 @default.
- W2952925259 hasRelatedWork W2537508289 @default.
- W2952925259 hasRelatedWork W2592407250 @default.
- W2952925259 hasRelatedWork W3028697823 @default.
- W2952925259 hasRelatedWork W3030480726 @default.
- W2952925259 hasVolume "237" @default.
- W2952925259 isParatext "false" @default.
- W2952925259 isRetracted "false" @default.
- W2952925259 magId "2952925259" @default.
- W2952925259 workType "article" @default.