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- W2953004501 abstract "Seven new prenylated indole diketopiperazines, versicamides A–G (1–7) and a novel chemical derivative from 7, versicamide H (8), along with three known analogic diketopiperazines (9–11) were obtained from the marine-derived fungus Aspergillus versicolor HDN08-60. Their structures were determined by spectroscopic techniques, including 2D NMR, ECD calculations, and single-crystal X-ray diffraction analysis, together with the assistance of further chemical conversions. The cytotoxicities of 1–8 were tested against the HeLa, HCT-116, HL-60, and K562 cell lines, but only 8 exhibited moderate activity against HL-60 cells, with an IC50 value of 8.7 μM. Further investigation with target screening showed that 8 exhibited selective PTK inhibitory activities." @default.
- W2953004501 created "2019-06-27" @default.
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- W2953004501 date "2015-02-19" @default.
- W2953004501 modified "2023-09-24" @default.
- W2953004501 title "ChemInform Abstract: Prenylated Indole Diketopiperazines from the Marine-Derived Fungus Aspergillus versicolor." @default.
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- W2953004501 doi "https://doi.org/10.1002/chin.201510273" @default.
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