FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953007060> ?p ?o ?g. }

• W2953007060 abstract "Background Adult spondyloarthritis (SpA) is characterized by abnormal bone overgrowth and inflammatory erosive osteopenia in the spine. SpA may be associated with psoriasis and psoriatic arthritis (PsA), inflammatory bowel disease, reactive arthritis, enthesitis, and ocular features such as acute anterior iritis, and chronic uveitis. Juvenile SpA onsets in children under 16 years old and may present with more peripheral enthesopathies and arthritis than adult SpA. Objectives This meta-analysis investigated the frequency and type of ocular involvement in childhood and adult SpA. The difference in frequency between childhood and adult SpA was also investigated. Methods Medline, Web of Science and Cochrane databases were searched to September, 2018 to identify publications related to spondyloarthropathy (SpA), and ankylosing spondylitis (AS) with ocular conditions (OC) (conjunctivitis, keratoconjunctivitis sicca, xeropthalmia, uveitis, eye hemorrhage, optic neuritis, papilledema, orbital disease, retinal artery/vein occlusion, macular edema, retinitis, chorioretinitis, scleritis, iridocyclitits, choroid hemorrhage, blindness and amaurosis fugax). The rates of OC were extracted and random effects models estimated their frequency. Heterogeneity was evaluated using I2. Inclusion criteria were studies in SpA of either children or adults that included a frequency of OC. Differences in frequencies of OC between childhood and adult disease were compared using chi squared tests. Results The search process identified 3164 articles, of which 41 were eligible for inclusion. A pooled random effects model showed the prevalence of uveitis was 24% [20%-27%] in adult AS (23 studies, N= 11943 patients), 10% [7%-14%] in adult PsA (9 studies, N=1817), and 17% [10%-24%] in undifferentiated adult SpA (9 studies, 6568 patients). In juveniles with AS, the prevalence of uveitis was 27% [16%-39%] (8 studies, 927 patients). In child onset PsA, uveitis occurred in 16% [10%-21%] (5 studies, N=498), and in juvenile undifferentiated SpA, uveitis had a frequency of 7% [1%-12%] (2 studies, N=1531). The differences in frequency of uveitis in adults vs. child onset SpA spectrum diseases were not significantly different between AS and JAS (p=0.891), PsA and JPsA (p=0.732) and between SpA and JSpA. Conclusion This meta-analysis compares the frequency of ocular involvement in seronegative spectrum diseases in adults and children where it appears that the frequency of uveitis is not statistically different in adult vs. child onset SpA and the subsets. References [1] Reveille JD, Weisman MH. The epidemiology of back pain, axial spondyloarthritis and HLA-B27 in the United States. Am J Med Sci2013;345:431-6. [2] Smith JA. Update on ankylosing spondylitis: current concepts in pathogenesis. Curr Allergy Asthma Rep2015;15:489. [3] Stolwijk C, Essers I, van Tubergen A, Boonen A, Bazelier MT, De Bruin ML, et al. The epidemiology of extra-articular manifestations in ankylosing spondylitis: a population-based matched cohort study. Annals of the Rheumatic Diseases2015;74:1373-8. [4] Lin Y-C, Liang T-H, Chen W-S, Lin H-Y. Differences between juvenile-onset ankylosing spondylitis and adult-onset ankylosing spondylitis. J Chin Med Assoc2009;72:573-80. [5] Cantini F, Nannini C, Cassara E, Kaloudi O, Niccoli L. Uveitis in Spondyloarthritis: An Overview. J Rheumatol Suppl2015;93:27-9. Disclosure of Interests Matthew Turk: None declared, Jacqueline Hayworth: None declared, Tatiana Nevskaya: None declared, Janet Pope Consultant for: Eli Lilly and Company" @default.
• W2953007060 created "2019-06-27" @default.
• W2953007060 creator A5002867301 @default.
• W2953007060 creator A5023213876 @default.
• W2953007060 creator A5073116893 @default.
• W2953007060 creator A5078422277 @default.
• W2953007060 date "2019-06-01" @default.
• W2953007060 modified "2023-09-26" @default.
• W2953007060 title "SAT0352 THE FREQUENCY OF OCULAR MANIFESTATIONS IN PATIENTS WITH ADULT VS. CHILDHOOD SPONDYLOARTHRITIS" @default.
• W2953007060 doi "https://doi.org/10.1136/annrheumdis-2019-eular.2434" @default.
• W2953007060 hasPublicationYear "2019" @default.
• W2953007060 type Work @default.
• W2953007060 sameAs 2953007060 @default.
• W2953007060 citedByCount "1" @default.
• W2953007060 countsByYear W29530070602021 @default.
• W2953007060 crossrefType "proceedings-article" @default.
• W2953007060 hasAuthorship W2953007060A5002867301 @default.
• W2953007060 hasAuthorship W2953007060A5023213876 @default.
• W2953007060 hasAuthorship W2953007060A5073116893 @default.
• W2953007060 hasAuthorship W2953007060A5078422277 @default.
• W2953007060 hasBestOaLocation W29530070601 @default.
• W2953007060 hasConcept C118487528 @default.
• W2953007060 hasConcept C126322002 @default.
• W2953007060 hasConcept C141071460 @default.
• W2953007060 hasConcept C2776194053 @default.
• W2953007060 hasConcept C2776661782 @default.
• W2953007060 hasConcept C2777077863 @default.
• W2953007060 hasConcept C2777462480 @default.
• W2953007060 hasConcept C2781053147 @default.
• W2953007060 hasConcept C71924100 @default.
• W2953007060 hasConceptScore W2953007060C118487528 @default.
• W2953007060 hasConceptScore W2953007060C126322002 @default.
• W2953007060 hasConceptScore W2953007060C141071460 @default.
• W2953007060 hasConceptScore W2953007060C2776194053 @default.
• W2953007060 hasConceptScore W2953007060C2776661782 @default.
• W2953007060 hasConceptScore W2953007060C2777077863 @default.
• W2953007060 hasConceptScore W2953007060C2777462480 @default.
• W2953007060 hasConceptScore W2953007060C2781053147 @default.
• W2953007060 hasConceptScore W2953007060C71924100 @default.
• W2953007060 hasLocation W29530070601 @default.
• W2953007060 hasOpenAccess W2953007060 @default.
• W2953007060 hasPrimaryLocation W29530070601 @default.
• W2953007060 hasRelatedWork W1494154451 @default.
• W2953007060 hasRelatedWork W1991755666 @default.
• W2953007060 hasRelatedWork W2040292063 @default.
• W2953007060 hasRelatedWork W2115631220 @default.
• W2953007060 hasRelatedWork W2128563477 @default.
• W2953007060 hasRelatedWork W2314298052 @default.
• W2953007060 hasRelatedWork W2314714514 @default.
• W2953007060 hasRelatedWork W2416027470 @default.
• W2953007060 hasRelatedWork W2417968633 @default.
• W2953007060 hasRelatedWork W2427792840 @default.
• W2953007060 hasRelatedWork W2552046944 @default.
• W2953007060 hasRelatedWork W2757655425 @default.
• W2953007060 hasRelatedWork W2884082065 @default.
• W2953007060 hasRelatedWork W2951103623 @default.
• W2953007060 hasRelatedWork W3035583143 @default.
• W2953007060 hasRelatedWork W3081733797 @default.
• W2953007060 hasRelatedWork W3152392295 @default.
• W2953007060 hasRelatedWork W78177450 @default.
• W2953007060 hasRelatedWork W986840306 @default.
• W2953007060 hasRelatedWork W2184133866 @default.
• W2953007060 isParatext "false" @default.
• W2953007060 isRetracted "false" @default.
• W2953007060 magId "2953007060" @default.
• W2953007060 workType "article" @default.