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- W2953034818 abstract "A novel simple method, based on treatment with isoamyl nitrite (IAN) in DMSO without any added acid, to produce selective C(5)-nitrosation of aminopyrimidine derivatives is described. It proved to be suitable for a multigram scale and applicable to a larger range of pyrimidine derivatives, including amino-dialkoxypyrimidines, than the procedures previously known. Its scope is analyzed and some example on the usefulness of the newly prepared substances as intermediates in the synthesis of fused heterobicyclic derivatives of potential biological interest is presented." @default.
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- W2953034818 date "2002-01-01" @default.
- W2953034818 modified "2023-09-23" @default.
- W2953034818 title "Novel Procedure for Selective C-Nitrosation of Aminopyrimidine Derivatives Under Neutral Conditions. Scope and Synthetic Applications" @default.
- W2953034818 doi "https://doi.org/10.1055/s-2002-19760" @default.
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