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- W2953066083 abstract "A series of 32-(O)-acylated and 32-(O)-thioacylated derivatives of the antibiotic ascomycin (1) have been synthesized. These readily accessible analogues exhibit potent immunosuppressive activity in vitro, as measured by an interleukin-2 reporter gene assay and the mixed lymphocyte reaction. Such molecules are expected to have a therapeutic potential in chronic inflammatory diseases of the airways such as asthma." @default.
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- W2953066083 date "1999-01-01" @default.
- W2953066083 modified "2023-09-25" @default.
- W2953066083 title "Preparation and immunosuppressive activity of 32-(O)-acylated and 32-(O)-thioacylated analogues of ascomycin" @default.
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- W2953066083 doi "https://doi.org/10.1016/s0960-894x(98)00702-1" @default.
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