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- W2953102117 abstract "Chemical study on the twigs and leaves of Croton tiglium has led to the isolation of 11 new tigliane-type diterpenoids, crotignoids A–K (1–11), along with eight known analogues (12–19). The structures of these compounds were elucidated on the basis of detailed spectroscopic analysis. In vitro cytotoxic assays revealed moderate inhibition of compounds 1–10 toward human HL-60 and A549 tumor cells, with 1 exhibiting the strongest activity against HL-60 cell line with an IC50 value of 1.61 μM." @default.
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- W2953102117 date "2015-12-01" @default.
- W2953102117 modified "2023-10-09" @default.
- W2953102117 title "Cytotoxic tigliane-type diterpenoids from Croton tiglium" @default.
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- W2953102117 doi "https://doi.org/10.1016/j.tet.2015.10.070" @default.
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