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- W2953164750 abstract "Two novel triterpenoids, lantadienone (1) and camaradienone (2), were isolated from the aerial parts of Lantana camara, along with seven known compounds, lantadene A, lantadene B, b-sitosterol 3-(b-d- glucopyranoside), camaric acid, lantanilic acid, lantanolic acid, and camangeloyl acid. Their structures were elucidated as (3b,22b)-3,25-epoxy-3-hydroxy-22-{((2Z)-2-methyl-1-oxobut-2-enyl)oxy}-28-nor- oleana-12,17-dien-11-one (1) and (3b)-3,25-epoxy-3-hydroxy-28-noroleana-12,17-dien-11-one (2), re- spectively, by means of spectral studies. The triterpenoids 1 and 2 represent 28-noroleananes oxidized at C(11) and C(22) or at C(11), reported for the first time. Introduction. - Lantana camara Linn. (family Verbenaceae) commonly known as lantana, is a hairy shrub, native of tropical America cultivated elsewhere as an ornamental or hedge plant. Different parts of the plant are used for the treatment of various human ailments, such as itches, cuts, ulcers, malaria, influenza, anemia, tumors, swellings, bilious fever, eczema eruptions, rheumatism, stomachache, toothache, scabies, leprosy, and as antiseptic for wounds. The aqueous extract of the leaves showed antihyperglycaemic activity and wound-healing property. Pharmacological investigations indicated that extracts of the shoot of L. camara exhibit antibacterial properties. Lancamarone, a steroid from the leaves, possesses cardiotonic properties, while lantamine, an alkaloid from the bark of stems and roots, shows strong antipyretic and antispasmodic properties comparable with those of quinine (1 - 4). Phytochemical studies undertaken by different research groups on different parts of the plant have resulted in the isolation of various terpenoids (3) (5), steroids (3), and flavonoids (3) (6). The present studies were undertaken on the chemical constituents of the aerial parts of this plant, which resulted in the isolation and structure elucidation of two new nortriterpenoids, lantadienone (1) and camaradienone (2), along with seven known compounds, lantadene A (¼ (22b)-22-{((2Z)-2-methyl-1-oxobut-2-enyl)oxy}-3-oxo-" @default.
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- W2953164750 date "2008-08-12" @default.
- W2953164750 modified "2023-09-24" @default.
- W2953164750 title "ChemInform Abstract: Noroleanane Triterpenoids from the Aerial Parts of Lantana camara." @default.
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- W2953164750 doi "https://doi.org/10.1002/chin.200833182" @default.
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