Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953198760> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2953198760 abstract "We describe a modular modelling approach permitting curation, updating, and distributed development of modules through joined community effort overcoming the problem of keeping a combinatorially exploding number of monolithic models up to date. For this purpose, the effects of genes and their mutated alleles on downstream components are modeled by composable, metadata-containing Petri net models organized in a database with version control, accessible through a web interface. Gene modules can be coupled to protein modules through mRNA modules by specific interfaces designed for the automatic, database-assisted composition. Automatically assembled executable models may then consider cell type-specific gene expression patterns and the resulting protein concentrations. Gene modules and allelic interference modules may represent effects of gene mutation and predict their pleiotropic consequences or uncover complex genotype/phenotype relationships. Forward and reverse engineered modules are fully compatible." @default.
- W2953198760 created "2019-06-27" @default.
- W2953198760 creator A5002026696 @default.
- W2953198760 creator A5002359152 @default.
- W2953198760 creator A5032551381 @default.
- W2953198760 date "2012-05-21" @default.
- W2953198760 modified "2023-10-01" @default.
- W2953198760 title "Predicting Phenotype from Genotype Through Automatically Composed Petri Nets" @default.
- W2953198760 cites W2036454804 @default.
- W2953198760 cites W2123333705 @default.
- W2953198760 cites W58859871 @default.
- W2953198760 hasPublicationYear "2012" @default.
- W2953198760 type Work @default.
- W2953198760 sameAs 2953198760 @default.
- W2953198760 citedByCount "0" @default.
- W2953198760 crossrefType "posted-content" @default.
- W2953198760 hasAuthorship W2953198760A5002026696 @default.
- W2953198760 hasAuthorship W2953198760A5002359152 @default.
- W2953198760 hasAuthorship W2953198760A5032551381 @default.
- W2953198760 hasConcept C101468663 @default.
- W2953198760 hasConcept C104317684 @default.
- W2953198760 hasConcept C111919701 @default.
- W2953198760 hasConcept C113843644 @default.
- W2953198760 hasConcept C120314980 @default.
- W2953198760 hasConcept C127716648 @default.
- W2953198760 hasConcept C129307140 @default.
- W2953198760 hasConcept C157915830 @default.
- W2953198760 hasConcept C160145156 @default.
- W2953198760 hasConcept C199360897 @default.
- W2953198760 hasConcept C2779478453 @default.
- W2953198760 hasConcept C38677869 @default.
- W2953198760 hasConcept C41008148 @default.
- W2953198760 hasConcept C54355233 @default.
- W2953198760 hasConcept C70721500 @default.
- W2953198760 hasConcept C77088390 @default.
- W2953198760 hasConcept C86803240 @default.
- W2953198760 hasConcept C93518851 @default.
- W2953198760 hasConceptScore W2953198760C101468663 @default.
- W2953198760 hasConceptScore W2953198760C104317684 @default.
- W2953198760 hasConceptScore W2953198760C111919701 @default.
- W2953198760 hasConceptScore W2953198760C113843644 @default.
- W2953198760 hasConceptScore W2953198760C120314980 @default.
- W2953198760 hasConceptScore W2953198760C127716648 @default.
- W2953198760 hasConceptScore W2953198760C129307140 @default.
- W2953198760 hasConceptScore W2953198760C157915830 @default.
- W2953198760 hasConceptScore W2953198760C160145156 @default.
- W2953198760 hasConceptScore W2953198760C199360897 @default.
- W2953198760 hasConceptScore W2953198760C2779478453 @default.
- W2953198760 hasConceptScore W2953198760C38677869 @default.
- W2953198760 hasConceptScore W2953198760C41008148 @default.
- W2953198760 hasConceptScore W2953198760C54355233 @default.
- W2953198760 hasConceptScore W2953198760C70721500 @default.
- W2953198760 hasConceptScore W2953198760C77088390 @default.
- W2953198760 hasConceptScore W2953198760C86803240 @default.
- W2953198760 hasConceptScore W2953198760C93518851 @default.
- W2953198760 hasLocation W29531987601 @default.
- W2953198760 hasOpenAccess W2953198760 @default.
- W2953198760 hasPrimaryLocation W29531987601 @default.
- W2953198760 hasRelatedWork W1713068554 @default.
- W2953198760 hasRelatedWork W2023465156 @default.
- W2953198760 hasRelatedWork W2024020323 @default.
- W2953198760 hasRelatedWork W2024060441 @default.
- W2953198760 hasRelatedWork W2025174715 @default.
- W2953198760 hasRelatedWork W2087167584 @default.
- W2953198760 hasRelatedWork W2108519121 @default.
- W2953198760 hasRelatedWork W226686742 @default.
- W2953198760 hasRelatedWork W2488202259 @default.
- W2953198760 hasRelatedWork W2511693152 @default.
- W2953198760 hasRelatedWork W2794507075 @default.
- W2953198760 hasRelatedWork W2798570041 @default.
- W2953198760 hasRelatedWork W2883256575 @default.
- W2953198760 hasRelatedWork W2913931952 @default.
- W2953198760 hasRelatedWork W2951380945 @default.
- W2953198760 hasRelatedWork W2959770407 @default.
- W2953198760 hasRelatedWork W2964444983 @default.
- W2953198760 hasRelatedWork W2965038981 @default.
- W2953198760 hasRelatedWork W3004201381 @default.
- W2953198760 hasRelatedWork W2166505777 @default.
- W2953198760 isParatext "false" @default.
- W2953198760 isRetracted "false" @default.
- W2953198760 magId "2953198760" @default.
- W2953198760 workType "article" @default.