Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953202427> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2953202427 endingPage "1201" @default.
- W2953202427 startingPage "1195" @default.
- W2953202427 abstract "The first asymmetric synthesis of potential cyclic urea HIV protease inhibitors of Type 2 is reported. The synthesis is short and highly versatile in the choice of the substitution pattern and absolute configuration of the products starting from readily available materials. Nonchiral central building block 5 was synthesized and subsequently asymmetrically alkylated under (R)-/(S)-1-amino-2-(methoxymethyl)pyrrolidine (RAMP/SAMP)-auxiliary control to provide 8a – e. The alkylated ketones then were reduced to the target compounds 9a – e, with good-to-excellent overall yields, as well as diastereoisomeric and enantiomeric purities." @default.
- W2953202427 created "2019-06-27" @default.
- W2953202427 creator A5077398318 @default.
- W2953202427 creator A5080612612 @default.
- W2953202427 creator A5088517982 @default.
- W2953202427 creator A5088754757 @default.
- W2953202427 date "1999-08-04" @default.
- W2953202427 modified "2023-10-16" @default.
- W2953202427 title "Asymmetric Synthesis of 1,2,3,4,5,6-Hexahydro-5-hydroxypyrimidin-2-ones as Potential HIV-Protease Inhibitors" @default.
- W2953202427 doi "https://doi.org/10.1002/(sici)1522-2675(19990804)82:8<1195::aid-hlca1195>3.0.co;2-n" @default.
- W2953202427 hasPublicationYear "1999" @default.
- W2953202427 type Work @default.
- W2953202427 sameAs 2953202427 @default.
- W2953202427 citedByCount "13" @default.
- W2953202427 countsByYear W29532024272014 @default.
- W2953202427 countsByYear W29532024272022 @default.
- W2953202427 crossrefType "journal-article" @default.
- W2953202427 hasAuthorship W2953202427A5077398318 @default.
- W2953202427 hasAuthorship W2953202427A5080612612 @default.
- W2953202427 hasAuthorship W2953202427A5088517982 @default.
- W2953202427 hasAuthorship W2953202427A5088754757 @default.
- W2953202427 hasConcept C146686406 @default.
- W2953202427 hasConcept C161790260 @default.
- W2953202427 hasConcept C164361826 @default.
- W2953202427 hasConcept C178790620 @default.
- W2953202427 hasConcept C181199279 @default.
- W2953202427 hasConcept C185592680 @default.
- W2953202427 hasConcept C21951064 @default.
- W2953202427 hasConcept C2776714187 @default.
- W2953202427 hasConcept C2777583353 @default.
- W2953202427 hasConcept C2778851528 @default.
- W2953202427 hasConcept C2780365088 @default.
- W2953202427 hasConcept C486523 @default.
- W2953202427 hasConcept C71240020 @default.
- W2953202427 hasConceptScore W2953202427C146686406 @default.
- W2953202427 hasConceptScore W2953202427C161790260 @default.
- W2953202427 hasConceptScore W2953202427C164361826 @default.
- W2953202427 hasConceptScore W2953202427C178790620 @default.
- W2953202427 hasConceptScore W2953202427C181199279 @default.
- W2953202427 hasConceptScore W2953202427C185592680 @default.
- W2953202427 hasConceptScore W2953202427C21951064 @default.
- W2953202427 hasConceptScore W2953202427C2776714187 @default.
- W2953202427 hasConceptScore W2953202427C2777583353 @default.
- W2953202427 hasConceptScore W2953202427C2778851528 @default.
- W2953202427 hasConceptScore W2953202427C2780365088 @default.
- W2953202427 hasConceptScore W2953202427C486523 @default.
- W2953202427 hasConceptScore W2953202427C71240020 @default.
- W2953202427 hasIssue "8" @default.
- W2953202427 hasLocation W29532024271 @default.
- W2953202427 hasOpenAccess W2953202427 @default.
- W2953202427 hasPrimaryLocation W29532024271 @default.
- W2953202427 hasRelatedWork W1956888186 @default.
- W2953202427 hasRelatedWork W1966835439 @default.
- W2953202427 hasRelatedWork W2006038166 @default.
- W2953202427 hasRelatedWork W2026709745 @default.
- W2953202427 hasRelatedWork W2030839456 @default.
- W2953202427 hasRelatedWork W2063822755 @default.
- W2953202427 hasRelatedWork W2319867291 @default.
- W2953202427 hasRelatedWork W2950147591 @default.
- W2953202427 hasRelatedWork W2950610275 @default.
- W2953202427 hasRelatedWork W4366245638 @default.
- W2953202427 hasVolume "82" @default.
- W2953202427 isParatext "false" @default.
- W2953202427 isRetracted "false" @default.
- W2953202427 magId "2953202427" @default.
- W2953202427 workType "article" @default.