FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953204044> ?p ?o ?g. }

• W2953204044 endingPage "1487" @default.
• W2953204044 startingPage "1481" @default.
• W2953204044 abstract "1,4-Thiazepines derivatives are pharmacologically important heterocycles with different applications in medicinal chemistry. In the present work, we describe the preparation of new bicyclic thiazolidinyl-1,4-thiazepines 3 by reaction between azadithiane compounds and Michael acceptors. The reaction scope was explored and the yields were optimized. The activity of the new compounds was evaluated against Nippostrongylus brasiliensis and Caenorhabditis elegans as anthelmintic models and Trypanosoma brucei brucei. The most active compound was 3l, showing an EC50 = 2.8 ± 0.7 μM against T. b. brucei and a selectivity index >71." @default.
• W2953204044 created "2019-06-27" @default.
• W2953204044 creator A5002533565 @default.
• W2953204044 creator A5012704166 @default.
• W2953204044 creator A5026701214 @default.
• W2953204044 creator A5028091391 @default.
• W2953204044 creator A5035889583 @default.
• W2953204044 creator A5040633215 @default.
• W2953204044 creator A5045828545 @default.
• W2953204044 creator A5046271139 @default.
• W2953204044 creator A5055439054 @default.
• W2953204044 creator A5073242651 @default.
• W2953204044 creator A5075343711 @default.
• W2953204044 creator A5078254221 @default.
• W2953204044 date "2019-01-01" @default.
• W2953204044 modified "2023-10-18" @default.
• W2953204044 title "Synthesis of bicyclic 1,4-thiazepines as novel anti-<i>Trypanosoma brucei brucei</i> agents" @default.
• W2953204044 cites W1156765303 @default.
• W2953204044 cites W1875197001 @default.
• W2953204044 cites W1969487950 @default.
• W2953204044 cites W1975710243 @default.
• W2953204044 cites W1989266032 @default.
• W2953204044 cites W2007688577 @default.
• W2953204044 cites W2012961504 @default.
• W2953204044 cites W2044575523 @default.
• W2953204044 cites W2047109556 @default.
• W2953204044 cites W2059678352 @default.
• W2953204044 cites W2064665921 @default.
• W2953204044 cites W2065793802 @default.
• W2953204044 cites W2074274985 @default.
• W2953204044 cites W2077010275 @default.
• W2953204044 cites W2079440932 @default.
• W2953204044 cites W2087899477 @default.
• W2953204044 cites W2096095251 @default.
• W2953204044 cites W2106307542 @default.
• W2953204044 cites W2126572041 @default.
• W2953204044 cites W2135732933 @default.
• W2953204044 cites W2136845654 @default.
• W2953204044 cites W2221606817 @default.
• W2953204044 cites W2314612202 @default.
• W2953204044 cites W2317810175 @default.
• W2953204044 cites W2410196292 @default.
• W2953204044 cites W2415189273 @default.
• W2953204044 cites W2536793719 @default.
• W2953204044 cites W2559420899 @default.
• W2953204044 cites W2782562383 @default.
• W2953204044 cites W2950831804 @default.
• W2953204044 cites W2951308440 @default.
• W2953204044 cites W75076976 @default.
• W2953204044 doi "https://doi.org/10.1039/c9md00064j" @default.
• W2953204044 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6786244" @default.
• W2953204044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31673311" @default.
• W2953204044 hasPublicationYear "2019" @default.
• W2953204044 type Work @default.
• W2953204044 sameAs 2953204044 @default.
• W2953204044 citedByCount "5" @default.
• W2953204044 countsByYear W29532040442020 @default.
• W2953204044 countsByYear W29532040442021 @default.
• W2953204044 countsByYear W29532040442023 @default.
• W2953204044 crossrefType "journal-article" @default.
• W2953204044 hasAuthorship W2953204044A5002533565 @default.
• W2953204044 hasAuthorship W2953204044A5012704166 @default.
• W2953204044 hasAuthorship W2953204044A5026701214 @default.
• W2953204044 hasAuthorship W2953204044A5028091391 @default.
• W2953204044 hasAuthorship W2953204044A5035889583 @default.
• W2953204044 hasAuthorship W2953204044A5040633215 @default.
• W2953204044 hasAuthorship W2953204044A5045828545 @default.
• W2953204044 hasAuthorship W2953204044A5046271139 @default.
• W2953204044 hasAuthorship W2953204044A5055439054 @default.
• W2953204044 hasAuthorship W2953204044A5073242651 @default.
• W2953204044 hasAuthorship W2953204044A5075343711 @default.
• W2953204044 hasAuthorship W2953204044A5078254221 @default.
• W2953204044 hasBestOaLocation W29532040442 @default.
• W2953204044 hasConcept C104317684 @default.
• W2953204044 hasConcept C159047783 @default.
• W2953204044 hasConcept C185592680 @default.
• W2953204044 hasConcept C203014093 @default.
• W2953204044 hasConcept C21951064 @default.
• W2953204044 hasConcept C24961977 @default.
• W2953204044 hasConcept C2775952312 @default.
• W2953204044 hasConcept C2778944004 @default.
• W2953204044 hasConcept C2779502636 @default.
• W2953204044 hasConcept C2779549974 @default.
• W2953204044 hasConcept C55493867 @default.
• W2953204044 hasConcept C71240020 @default.
• W2953204044 hasConcept C86803240 @default.
• W2953204044 hasConcept C8891405 @default.
• W2953204044 hasConceptScore W2953204044C104317684 @default.
• W2953204044 hasConceptScore W2953204044C159047783 @default.
• W2953204044 hasConceptScore W2953204044C185592680 @default.
• W2953204044 hasConceptScore W2953204044C203014093 @default.
• W2953204044 hasConceptScore W2953204044C21951064 @default.
• W2953204044 hasConceptScore W2953204044C24961977 @default.
• W2953204044 hasConceptScore W2953204044C2775952312 @default.
• W2953204044 hasConceptScore W2953204044C2778944004 @default.
• W2953204044 hasConceptScore W2953204044C2779502636 @default.
• W2953204044 hasConceptScore W2953204044C2779549974 @default.
• W2953204044 hasConceptScore W2953204044C55493867 @default.

• next