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- W2953204804 abstract "We argue that the phenomenon of symmetry breaking in genetics can enhance the adaptability of a species to changes in the environment. In the case of a virus, the claim is that the codon bias in the neutralization epitope improves the virus' ability to generate mutants that evade the induced immune response. We support our claim with a simple ``toy model'' of a viral epitope evolving in competition with the immune system. The effective selective advantage of a higher mutability leads to a dominance of codons that favour non-synonymous mutations. The results in this paper suggest the possibility of emergence of an algorithmic language in more complicated systems." @default.
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- W2953204804 date "1997-08-06" @default.
- W2953204804 modified "2023-09-27" @default.
- W2953204804 title "Symmetry Breaking and Adaptation: Evidence from a Toy Model of a Virus" @default.
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