Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953208034> ?p ?o ?g. }
- W2953208034 endingPage "e0213616" @default.
- W2953208034 startingPage "e0213616" @default.
- W2953208034 abstract "There is convincing evidence that the deprivation of one sense can lead to adaptive neuronal changes in spared primary sensory cortices. However, the repercussions of late-onset sensory deprivations on functionality of the remaining sensory cortices are poorly understood. Using repeated intrinsic signal imaging we investigated the effects of whisker or auditory deprivation (WD or AD, respectively) on responsiveness of the binocular primary visual cortex (V1) in fully adult mice. The binocular zone of mice is innervated by both eyes, with the contralateral eye always dominating V1 input over ipsilateral eye input, the normal ocular dominance (OD) ratio. Strikingly, we found that 3 days of WD or AD induced a transient shift of OD, which was mediated by a potentiation of V1 input through the ipsilateral eye. This cross-modal effect was accompanied by strengthening of layer 4 synapses in V1, required visual experience through the ipsilateral eye and was mediated by an increase of the excitation/inhibition ratio in V1. Finally, we demonstrate that both WD and AD induced a long-lasting improvement of visual performance. Our data provide evidence that the deprivation of a non-visual sensory modality cross-modally induces experience dependent V1 plasticity and improves visual behavior, even in adult mice." @default.
- W2953208034 created "2019-06-27" @default.
- W2953208034 creator A5009733924 @default.
- W2953208034 creator A5033334285 @default.
- W2953208034 creator A5062676906 @default.
- W2953208034 creator A5063259918 @default.
- W2953208034 creator A5068686757 @default.
- W2953208034 creator A5082507843 @default.
- W2953208034 creator A5083533358 @default.
- W2953208034 creator A5085774551 @default.
- W2953208034 date "2019-03-11" @default.
- W2953208034 modified "2023-10-16" @default.
- W2953208034 title "Visual deprivation independent shift of ocular dominance induced by cross-modal plasticity" @default.
- W2953208034 cites W1184050146 @default.
- W2953208034 cites W1504798403 @default.
- W2953208034 cites W1521319725 @default.
- W2953208034 cites W1523136835 @default.
- W2953208034 cites W1726527000 @default.
- W2953208034 cites W1842266333 @default.
- W2953208034 cites W1870538900 @default.
- W2953208034 cites W1965513983 @default.
- W2953208034 cites W1966477239 @default.
- W2953208034 cites W1971604198 @default.
- W2953208034 cites W1975402449 @default.
- W2953208034 cites W1979344173 @default.
- W2953208034 cites W1982733111 @default.
- W2953208034 cites W1984715501 @default.
- W2953208034 cites W1988486491 @default.
- W2953208034 cites W2008744372 @default.
- W2953208034 cites W2010669646 @default.
- W2953208034 cites W2013377646 @default.
- W2953208034 cites W2019601077 @default.
- W2953208034 cites W2022970771 @default.
- W2953208034 cites W2029578047 @default.
- W2953208034 cites W2035661164 @default.
- W2953208034 cites W2036970711 @default.
- W2953208034 cites W2037043502 @default.
- W2953208034 cites W2037289953 @default.
- W2953208034 cites W2041984232 @default.
- W2953208034 cites W2047535883 @default.
- W2953208034 cites W2051423370 @default.
- W2953208034 cites W2055820698 @default.
- W2953208034 cites W2060287168 @default.
- W2953208034 cites W2065602929 @default.
- W2953208034 cites W2070132345 @default.
- W2953208034 cites W2080579546 @default.
- W2953208034 cites W2082407289 @default.
- W2953208034 cites W2088475496 @default.
- W2953208034 cites W2091116794 @default.
- W2953208034 cites W2094598304 @default.
- W2953208034 cites W2099880108 @default.
- W2953208034 cites W2104220712 @default.
- W2953208034 cites W2104508398 @default.
- W2953208034 cites W2105748689 @default.
- W2953208034 cites W2108488213 @default.
- W2953208034 cites W2108889104 @default.
- W2953208034 cites W2116468206 @default.
- W2953208034 cites W2117674180 @default.
- W2953208034 cites W2135364335 @default.
- W2953208034 cites W2156940776 @default.
- W2953208034 cites W2165750738 @default.
- W2953208034 cites W2168250667 @default.
- W2953208034 cites W2171223590 @default.
- W2953208034 cites W2263192676 @default.
- W2953208034 cites W2364069565 @default.
- W2953208034 cites W2529867006 @default.
- W2953208034 cites W2737559449 @default.
- W2953208034 cites W2752748050 @default.
- W2953208034 cites W2766063118 @default.
- W2953208034 cites W2767510644 @default.
- W2953208034 cites W2772678117 @default.
- W2953208034 cites W2774212355 @default.
- W2953208034 cites W2803708338 @default.
- W2953208034 cites W2806568135 @default.
- W2953208034 cites W2894188904 @default.
- W2953208034 cites W2904737051 @default.
- W2953208034 cites W2952770633 @default.
- W2953208034 cites W4230909833 @default.
- W2953208034 doi "https://doi.org/10.1371/journal.pone.0213616" @default.
- W2953208034 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6411125" @default.
- W2953208034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30856226" @default.
- W2953208034 hasPublicationYear "2019" @default.
- W2953208034 type Work @default.
- W2953208034 sameAs 2953208034 @default.
- W2953208034 citedByCount "9" @default.
- W2953208034 countsByYear W29532080342019 @default.
- W2953208034 countsByYear W29532080342020 @default.
- W2953208034 countsByYear W29532080342022 @default.
- W2953208034 countsByYear W29532080342023 @default.
- W2953208034 crossrefType "journal-article" @default.
- W2953208034 hasAuthorship W2953208034A5009733924 @default.
- W2953208034 hasAuthorship W2953208034A5033334285 @default.
- W2953208034 hasAuthorship W2953208034A5062676906 @default.
- W2953208034 hasAuthorship W2953208034A5063259918 @default.
- W2953208034 hasAuthorship W2953208034A5068686757 @default.
- W2953208034 hasAuthorship W2953208034A5082507843 @default.
- W2953208034 hasAuthorship W2953208034A5083533358 @default.
- W2953208034 hasAuthorship W2953208034A5085774551 @default.