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- W2953281992 abstract "The citric acid cycle (CAC) is recognized as the central hub of a large number of metabolic pathways. It is commonly known as the Krebs cycle or tricarboxylic acid cycle. It starts from the reaction between oxaloacetate and actyl CoA. It is an enzyme-controlled metabolic cycle involved in metabolizing of biomolecules. The main purpose of the CAC is to furnish the energy demand of all types of cells but its intermediates are used as precursors in the biosynthesis of metabolites, thus different metabolic pathways are joined with the CAC making a network of metabolic pathways. The utilization of CAC flux in energy generation or in the biosynthesis of a metabolite depends on the energy requirements of the cell and physiological conditions. The control and regulation of the CAC reactions have great significance in cell metabolism and the utilization of flux in biomolecule biosynthesis. Researchers are using CAC manipulations (metabolic engineering) to enhance the yield of desired metabolites by altering the flux of specific intermediates or the overexpression of enzymes to catalyze more product formation." @default.
- W2953281992 created "2019-06-27" @default.
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- W2953281992 date "2019-01-01" @default.
- W2953281992 modified "2023-10-16" @default.
- W2953281992 title "Citric Acid Cycle Regulation: Back Bone for Secondary Metabolite Production" @default.
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- W2953281992 doi "https://doi.org/10.1016/b978-0-444-63504-4.00013-x" @default.
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